Oxaziridine, 2-[(4-methylphenyl)sulfonyl]-3-(3-nitrophenyl)-, trans-

Base Information

• Chemical Name: Oxaziridine, 2-[(4-methylphenyl)sulfonyl]-3-(3-nitrophenyl)-, trans-
• CAS No.: 73890-33-2
• Molecular Formula: C₁₄H₁₂N₂O₅S
• Molecular Weight: 320.326
• Mol file: 73890-33-2.mol

Synonyms:

Chemical Property of Oxaziridine, 2-[(4-methylphenyl)sulfonyl]-3-(3-nitrophenyl)-, trans-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Oxaziridine, 2-[(4-methylphenyl)sulfonyl]-3-(3-nitrophenyl)-, trans-

There total 3 articles about Oxaziridine, 2-[(4-methylphenyl)sulfonyl]-3-(3-nitrophenyl)-, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

4-methyl-N-(3-nitrobenzylidene)benzenesulfonamide (73845-02-0) → 2-(p-toluenesulfonyl)-3-(m-nitrophenyl)oxaziridine (67995-01-1,73890-33-2)

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In chloroform; water; for 4h; m-chloroperbenzoic acid was added at 0 deg C over 45 min;

DOI:10.1021/ja00526a040

Reference yield:

3-nitro-benzaldehyde diethylacetal (2403-49-8) → 2-(p-toluenesulfonyl)-3-(m-nitrophenyl)oxaziridine (67995-01-1,73890-33-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / 0.5 h / 150 - 180 °C

2: 40 percent / NaHCO₃, m-chloroperbenzoic acid / CHCl₃; H₂O / 4 h / m-chloroperbenzoic acid was added at 0 deg C over 45 min

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In chloroform; water;

DOI:10.1021/ja00526a040

Reference yield:

toluene-4-sulfonamide (70-55-3) → 2-(p-toluenesulfonyl)-3-(m-nitrophenyl)oxaziridine (67995-01-1,73890-33-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / 0.5 h / 150 - 180 °C

2: 40 percent / NaHCO₃, m-chloroperbenzoic acid / CHCl₃; H₂O / 4 h / m-chloroperbenzoic acid was added at 0 deg C over 45 min

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In chloroform; water;

DOI:10.1021/ja00526a040

upstream raw materials:

4-methyl-N-(3-nitrobenzylidene)benzenesulfonamide

3-nitro-benzaldehyde diethylacetal

toluene-4-sulfonamide

Downstream raw materials:

4-methyl-N-(3-nitrobenzylidene)benzenesulfonamide

(1S)-(-)-thiofenchone S-oxide

Refernces