1-Chloro-3-hydroxynaphthalene

Base Information

• Chemical Name: 1-Chloro-3-hydroxynaphthalene
• CAS No.: 75907-51-6
• Molecular Formula: C10H7ClO
• Molecular Weight: 178.61500
• DSSTox Substance ID: DTXSID90436410
• Nikkaji Number: J1.612.025A
• Wikidata: Q82251679
• Mol file: 75907-51-6.mol

Synonyms:75907-51-6;4-chloronaphthalen-2-ol;1-Chloro-3-hydroxynaphthalene;1-Chloro-3-naphthol;4-chloro-2-naphthol;2-Naphthalenol, 4-chloro-;SCHEMBL6700617;DTXSID90436410;AKOS002679763;FT-0714913

Chemical Property of 1-Chloro-3-hydroxynaphthalene

Chemical Property:

• PSA: 20.23000
• LogP: 3.19880
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 178.0185425
• Heavy Atom Count: 12
• Complexity: 160

Purity/Quality:

97% ^*data from raw suppliers

1-CHLORO-3-HYDROXYNAPHTHALENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=C(C=C2Cl)O

Technology Process of 1-Chloro-3-hydroxynaphthalene

There total 6 articles about 1-Chloro-3-hydroxynaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-dichloro-[2]naphthol (75917-07-6) → 4-chloro-2-naphthol (75907-51-6)

Guidance literature:

With hydrogenchloride; acetic acid; tin(ll) chloride;

DOI:10.1039/jr9450000280

Reference yield:

4-chloro-2-hydroxy-naphthalene-1-diazonium-betaine → 4-chloro-2-naphthol (75907-51-6)

Guidance literature:

With ethanol; aluminium;

DOI:10.1039/jr9430000468

Reference yield:

β-naphthol (135-19-3) → 4-chloro-2-naphthol (75907-51-6)

Guidance literature:

Multi-step reaction with 3 steps

1: SO₂Cl₂; tetrachloromethane

2: HCl; glacial acetic acid

3: HCl; glacial acetic acid; SnCl₂+2H₂O

With hydrogenchloride; tetrachloromethane; sulfuryl dichloride; acetic acid; tin(ll) chloride;

DOI:10.1039/jr9450000280

upstream raw materials:

1,4-dichloro-[2]naphthol

hydrogenchloride

acetic acid

1,1-dichloronaphtalene-2(1H)-one

Downstream raw materials:

4-chloro-2-methoxynaphthalene

4-phenylnaphthalen-2-ol

(2-hydroxy-4-chloro-1-naphthyl)diphenylcarbinol

1-(diphenylmethylene)-4-chloro-2(1H)-naphthalenone