N-(2-(2-hydroxyethyl)-3-methoxyphenyl)pivalamide

Base Information

Chemical Name:N-(2-(2-hydroxyethyl)-3-methoxyphenyl)pivalamide
CAS No.:76093-72-6
Molecular Formula:C14H21NO3
Molecular Weight:251.326
Hs Code.:
DSSTox Substance ID:DTXSID40506314
Wikidata:Q82362014

Synonyms:76093-72-6;N-(2-(2-hydroxyethyl)-3-methoxyphenyl)pivalamide;N-[2-(2-Hydroxyethyl)-3-methoxyphenyl]-2,2-dimethylpropanamide;N-[2-(2-hydroxyethyl)-3-methoxy-phenyl]-2,2-dimethyl-propanamide;Propanamide, N-[2-(2-hydroxyethyl)-3-methoxyphenyl]-2,2-dimethyl-;SCHEMBL3128204;DTXSID40506314;VLQCFCOZILVCKP-UHFFFAOYSA-N;BDA09372;MFCD21090869;AKOS005263931;SB74159;2-(2-hydroxyethyl)-3-pivalamidoanisole;AS-71916;CS-0038512;W12113;N-(-2(2-Hydroxyethyl)-3-Methoxyphenyl)Pivalamide

Suppliers and Price of N-(2-(2-hydroxyethyl)-3-methoxyphenyl)pivalamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N-(2-(2-hydroxyethyl)-3-methoxyphenyl)pivalamide

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:251.15214353
Heavy Atom Count:18
Complexity:273

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)NC1=C(C(=CC=C1)OC)CCO

Technology Process of N-(2-(2-hydroxyethyl)-3-methoxyphenyl)pivalamide

There total 6 articles about N-(2-(2-hydroxyethyl)-3-methoxyphenyl)pivalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.1%

: 75-21-8,99932-75-9
oxirane

: 56619-93-3
N-(3-methoxyphenyl)pivalamide

: 76093-72-6
N-[2-(2-hydroxyethyl)-3-methoxyphenyl]pivalamide

Guidance literature:: N-(3-methoxyphenyl)pivalamide; With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 2h; Inert atmosphere;

oxirane; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 3h;

Reference yield: 65.0%

: 75-21-8,99932-75-9
oxirane

: 76093-72-6
N-[2-(2-hydroxyethyl)-3-methoxyphenyl]pivalamide

Guidance literature:: N-(3-methoxyphenyl)pivalamide; With n-butyllithium; In tetrahydrofuran; at 0 - 22 ℃; for 24h;

oxirane; In tetrahydrofuran; at 0 ℃;

Reference yield:

: 3282-30-2
pivaloyl chloride

: 76093-72-6
N-[2-(2-hydroxyethyl)-3-methoxyphenyl]pivalamide

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / pyridine

2: 69 percent / n-BuLi / tetrahydrofuran; hexane / 1) 0 deg C, 1 h, 2) RT, 1 h

With n-butyllithium; In tetrahydrofuran; pyridine; hexane;