5-Vinyl-1H-indole

Base Information

• Chemical Name: 5-Vinyl-1H-indole
• CAS No.: 77132-99-1
• Molecular Formula: C10H9N
• Molecular Weight: 143.188
• DSSTox Substance ID: DTXSID40504299
• Nikkaji Number: J2.423.141K
• Wikidata: Q82358698
• Mol file: 77132-99-1.mol

Synonyms:5-Vinyl-1H-indole;77132-99-1;5-Ethenyl-1H-indole;5-vinylindole;SCHEMBL2419333;DTXSID40504299;ASAAYQMSBGYWLR-UHFFFAOYSA-N;CDA13299;AKOS006349729;BS-25948;EN300-387519;A1-10589

Chemical Property of 5-Vinyl-1H-indole

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 143.073499291
• Heavy Atom Count: 11
• Complexity: 153

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CC1=CC2=C(C=C1)NC=C2

Technology Process of 5-Vinyl-1H-indole

There total 3 articles about 5-Vinyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

5-ethyl-1H-indole-2-carboxylic acid (37033-93-5) → 5-ethyl-1H-indole (68742-28-9) + 5-ethenyl-1H-indole (77132-99-1)

Guidance literature:

K-16; In benzene; at 550 ℃;

DOI:10.1007/BF00473995

Reference yield: 21.0%

ethyl 5-ethylindole-2-carboxylate (37033-94-6) → 5-ethyl-1H-indole (68742-28-9) + 5-ethenyl-1H-indole (77132-99-1)

Guidance literature:

K-16; In benzene; at 550 ℃;

DOI:10.1007/BF00473995

Reference yield:

5-ethyl-1H-indole (68742-28-9) → indole (120-72-9) + 5-methyl-1H-indole (614-96-0) + 5-ethenyl-1H-indole (77132-99-1)

Guidance literature:

K-16; In benzene; at 550 ℃; for 6h; under 735.5 Torr; Product distribution; Various temperatures and concentrations of catalyst and 5-ethylindole;

upstream raw materials:

5-ethyl-1H-indole

5-ethyl-1H-indole-2-carboxylic acid

ethyl 5-ethylindole-2-carboxylate

Downstream raw materials:

5-ethyl-1H-indole

(E)-N-(2-(5-(3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-1-en-1-yl)-1H-indol-1-yl)-2-oxoethyl)-3,3,3-trifluoropropanamide

(E)-2-Amino-1-(5-(3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-1-enyl)-1H-indol-1-yl)ethanone

(E)-N-(2-(5-(3-(3,5-Dichloro-4-fluorophenyl)-4,4,4-trifluorobut-1-en-1-yl)-1H-indol-1-yl)-2-oxoethyl)-3,3,3-trifluoropropanamide