1-(2-((Dimethylamino)methyl)-4-methoxyphenyl)ethanone

Base Information

Chemical Name:1-(2-((Dimethylamino)methyl)-4-methoxyphenyl)ethanone
CAS No.:77973-25-2
Molecular Formula:C12H17NO2
Molecular Weight:207.26900
Hs Code.:2922509090
DSSTox Substance ID:DTXSID40504491
Wikidata:Q82359032
Mol file:77973-25-2.mol

Synonyms:77973-25-2;1-(2-((Dimethylamino)methyl)-4-methoxyphenyl)ethanone;1-(2-DIMETHYLAMINOMETHYL-4-METHOXY-PHENYL)-ETHANONE;1-[2-[(dimethylamino)methyl]-4-methoxyphenyl]ethanone;1-{2-[(Dimethylamino)methyl]-4-methoxyphenyl}ethan-1-one;1-(2-((dimethylamino)methyl)-4-methoxyphenyl)ethan-1-one;DTXSID40504491;CDA97325;MFCD09030510;AKOS015963647;SB77834;AC-17981;AS-69290;CS-0155087;D83330

Suppliers and Price of 1-(2-((Dimethylamino)methyl)-4-methoxyphenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
1-(2-Dimethylaminomethyl-4-methoxy-phenyl)-ethanone
5g
$ 1728.00

Rieke Metals
1-(2-Dimethylaminomethyl-4-methoxy-phenyl)-ethanone
1g
$ 661.00

Crysdot
1-(2-((Dimethylamino)methyl)-4-methoxyphenyl)ethanone 95+%
1g
$ 429.00

American Custom Chemicals Corporation
1-(2-DIMETHYLAMINOMETHYL-4-METHOXY-PHENYL)-ETHANONE 95.00%
5MG
$ 504.82

Alichem
1-(2-((Dimethylamino)methyl)-4-methoxyphenyl)ethanone
1g
$ 364.00

Total 4 raw suppliers

Chemical Property of 1-(2-((Dimethylamino)methyl)-4-methoxyphenyl)ethanone

Chemical Property:

Vapor Pressure:0.000455mmHg at 25°C
Boiling Point:314.8oC at 760 mmHg
Flash Point:144.2oC
PSA：29.54000
Density:1.028g/cm3
LogP:1.95940
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:207.125928785
Heavy Atom Count:15
Complexity:216

Purity/Quality:

99% ^*data from raw suppliers

1-(2-Dimethylaminomethyl-4-methoxy-phenyl)-ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C=C(C=C1)OC)CN(C)C

Technology Process of 1-(2-((Dimethylamino)methyl)-4-methoxyphenyl)ethanone

There total 5 articles about 1-(2-((Dimethylamino)methyl)-4-methoxyphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 75-36-5
acetyl chloride

: 77973-25-2
1-(2-dimethylaminomethyl-4-methoxyphenyl)ethanone

Guidance literature:: In 1,2-dichloro-ethane; for 12h; Heating;
DOI:10.1016/0040-4039(81)80072-X

Reference yield: 80.0%

: 111-34-2,92680-80-3
-butyl vinyl ether

: 10126-37-1
(2-bromo-5-methoxyphenyl)-N,N-dimethylmethanamine

: 77973-25-2
1-(2-dimethylaminomethyl-4-methoxyphenyl)ethanone

Guidance literature:: -butyl vinyl ether; (2-bromo-5-methoxyphenyl)-N,N-dimethylmethanamine; With palladium diacetate; 1,3-bis-(diphenylphosphino)propane; potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃;

With hydrogenchloride; In N,N-dimethyl-formamide; for 1h;
DOI:10.1021/jm049424k

Reference yield:

: 56658-04-9
2-bromo-5-methoxybenzoyl chloride

: 77973-25-2
1-(2-dimethylaminomethyl-4-methoxyphenyl)ethanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: H₂O / 1 h

2.1: 16.1 g / BH₃ / tetrahydrofuran / 5 h

3.1: Pd(OAc)2; 1,3-bis(diphenylphosphino)propane; aq. K₂CO₃ / dimethylformamide / 80 °C

3.2: 80 percent / aq. HCl / dimethylformamide / 1 h

With palladium diacetate; 1,3-bis-(diphenylphosphino)propane; borane; potassium carbonate; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1021/jm049424k