Diethyl bis(3-chloropropyl)propanedioate

Base Information

Chemical Name:Diethyl bis(3-chloropropyl)propanedioate
CAS No.:79899-30-2
Molecular Formula:C₁₃H₂₂Cl₂O₄
Molecular Weight:313.221
Hs Code.:
DSSTox Substance ID:DTXSID10511995
Wikidata:Q82371064

Synonyms:diethyl bis(3-chloropropyl)malonate;79899-30-2;Diethyl bis(3-chloropropyl)propanedioate;SCHEMBL722316;DTXSID10511995

Suppliers and Price of Diethyl bis(3-chloropropyl)propanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Diethyl bis(3-chloropropyl)propanedioate

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:12
Exact Mass:312.0895146
Heavy Atom Count:19
Complexity:254

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CCCCl)(CCCCl)C(=O)OCC

Technology Process of Diethyl bis(3-chloropropyl)propanedioate

There total 1 articles about Diethyl bis(3-chloropropyl)propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 109-70-6
1.3-chlorobromopropane

: 105-53-3
diethyl malonate

: 18719-43-2
diethyl (3-chloropropyl)malonate

: 79899-30-2
diethyl bis(3-chloropropyl)malonate

Guidance literature:: With sodium ethanolate;

Reference yield:

: 79899-30-2
diethyl bis(3-chloropropyl)malonate

: 79899-39-1
bis<2-<3-benzylthio)propyl>-5-(benzylthio)pentyl> trisuilfide

Guidance literature:: Multi-step reaction with 7 steps

1: 83 percent / trimethylsilyl iodide / CCl₄ / 120 h / 50 °C

2: 52 percent / 1 h / 170 °C

3: 96 percent / BH₃*Me₂S / diethyl ether / 5 h

4: 1.) CH₃ONa / 1.) CH₃OH, 2.) 25 deg C, 24 h

5: pyridine / 23 h / 5 °C

6: 19 percent / dimethylformamide / 24 h / 60 °C

7: 52 percent / Na₂S*9H₂O / methanol / 0.5 h / 5 °C

With pyridine; sodium sulfide; trimethylsilyl iodide; dimethylsulfide borane complex; sodium methylate; In methanol; tetrachloromethane; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jo00341a008

Reference yield:

: 79899-30-2
diethyl bis(3-chloropropyl)malonate

: 79899-37-9
2-(3-chloropropyl)-5-chloropentyl p-toluenesulfonate

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / trimethylsilyl iodide / CCl₄ / 120 h / 50 °C

2: 52 percent / 1 h / 170 °C

3: 96 percent / BH₃*Me₂S / diethyl ether / 5 h

4: 65 percent / pyridine / 144 h / 5 °C

With pyridine; trimethylsilyl iodide; dimethylsulfide borane complex; In tetrachloromethane; diethyl ether;
DOI:10.1021/jo00341a008