Phosphine, [2-oxo-2-[(trimethylstannyl)oxy]ethyl]diphenyl-

Base Information

• Chemical Name: Phosphine, [2-oxo-2-[(trimethylstannyl)oxy]ethyl]diphenyl-
• CAS No.: 800377-04-2
• Molecular Formula: C₁₇H₂₁O₂PSn
• Molecular Weight: 407.036
• Mol file: 800377-04-2.mol

Synonyms:

Chemical Property of Phosphine, [2-oxo-2-[(trimethylstannyl)oxy]ethyl]diphenyl-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phosphine, [2-oxo-2-[(trimethylstannyl)oxy]ethyl]diphenyl-

There total 1 articles about Phosphine, [2-oxo-2-[(trimethylstannyl)oxy]ethyl]diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

trimethyltin(IV)chloride (1066-45-1) + diphenylphosphinoacetic acid (3064-56-0) → trimethylstannyl (diphenylphosphino)acetate (800377-04-2)

Guidance literature:

With potassium tert-butoxide; In dichloromethane; under Ar; KO-t-Bu added to soln. of Ph2PCH2COOH in CH2Cl2; stirred at room temp. for 1 h; soln. of Me3SnCl in CH2Cl2 introduced; stirred overnight; diluted with hexane; stored for 1 h; filtered; filtrate evapd.; dried under vac.; elem. anal.;

DOI:10.1016/j.jorganchem.2004.07.060

Reference yield: 90.0%

dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer + trimethylstannyl (diphenylphosphino)acetate (800377-04-2) → chloro-((diphenylphosphino)acetate-κ2P,O)(η5-pentamethylcyclopentadienyl)rhodium(III)-trimethylstannyl chloride (800377-07-5)

Guidance literature:

In dichloromethane; under Ar; Rh complex and Sn compd. dissolved in CH2Cl2; stirred overnight; layered with hexane; crystd. by liq. phase diffusion over several d; elem. anal.;

DOI:10.1016/j.jorganchem.2004.07.060

Reference yield: 84.0%

trimethylstannyl (diphenylphosphino)acetate (800377-04-2) + trans-bis((μ-chloro)chloro-tri(2-furyl)phosphinepalladium(II)) (800377-05-3) → [SP-4-3]-chloro-((diphenylphosphino)acetate-κ2P,O)-tri(2-furyl)phosphinepalladium(II) (800377-06-4)

Guidance literature:

In dichloromethane; byproducts: Me3SnCl; under Ar; soln. of Sn compd. in CH2Cl2 added to soln. of Pd complex in CH2Cl2; stirred at room temp. for 2 d; evapd. under reduced pressure; washed with Et2O; dried under vac.; purified by dissolving in CH2Cl2 and pptn. with hexane; elem. anal.;

DOI:10.1016/j.jorganchem.2004.07.060

upstream raw materials:

trimethyltin(IV)chloride

diphenylphosphinoacetic acid

Downstream raw materials:

cis-bis((diphenylphosphino)acetate-κ2P,O)palladium(II)

chloro-((diphenylphosphino)acetate-κ2P,O)(η5-pentamethylcyclopentadienyl)rhodium(III)-trimethylstannyl chloride

[SP-4-3]-chloro-((diphenylphosphino)acetate-κ2P,O)-tri(2-furyl)phosphinepalladium(II)

cis-bis((diphenylphosphino)acetate-κ2P,O)platinum(II)