Tert-butyl 3-oxo-2-phenylpyrrolidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 3-oxo-2-phenylpyrrolidine-1-carboxylate
CAS No.:801282-28-0
Molecular Formula:C15H19NO3
Molecular Weight:261.321
Hs Code.:
European Community (EC) Number:886-180-9

Synonyms:Tert-butyl 3-oxo-2-phenylpyrrolidine-1-carboxylate;801282-28-0;tert-Butyl 3-oxo-2-phenyl-1-pyrrolidinecarboxylate;starbld0024884;EN300-7544482

Suppliers and Price of Tert-butyl 3-oxo-2-phenylpyrrolidine-1-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Tert-butyl 3-oxo-2-phenylpyrrolidine-1-carboxylate

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:261.13649347
Heavy Atom Count:19
Complexity:353

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(=O)C1C2=CC=CC=C2

Technology Process of Tert-butyl 3-oxo-2-phenylpyrrolidine-1-carboxylate

There total 4 articles about Tert-butyl 3-oxo-2-phenylpyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1027391-26-9
3-methoxy-2-phenyl-3-trimethylsilanyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester

: 801282-28-0
1-Boc-2-phenylpyrrolidin-3-one

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 1h;
DOI:10.1021/jo0488917

Reference yield:

: 100-52-7
benzaldehyde

: 801282-28-0
1-Boc-2-phenylpyrrolidin-3-one

Guidance literature:: Multi-step reaction with 4 steps

1: magnesium sulfate / CH₂Cl₂ / 20 °C

2: Et₃N; Bu₄NClO₄ / tetrahydrofuran / 20 °C / Electrochemical reaction

3: aq. NaHCO₃ / diethyl ether / 1 h / 20 °C

4: HCl / dioxane / 1 h / 20 °C

With hydrogenchloride; tetrabutylammonium perchlorate; sodium hydrogencarbonate; magnesium sulfate; triethylamine; In tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane;
DOI:10.1021/jo0488917

Reference yield:

: 138495-06-4
N-benzyliden-β-alanine methyl ester

: 801282-28-0
1-Boc-2-phenylpyrrolidin-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N; Bu₄NClO₄ / tetrahydrofuran / 20 °C / Electrochemical reaction

2: aq. NaHCO₃ / diethyl ether / 1 h / 20 °C

3: HCl / dioxane / 1 h / 20 °C

With hydrogenchloride; tetrabutylammonium perchlorate; sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; 1,4-dioxane; diethyl ether;
DOI:10.1021/jo0488917