3-(4-Nitrophenylamino)-1,3-diphenylpropan-1-one

Base Information

Chemical Name:3-(4-Nitrophenylamino)-1,3-diphenylpropan-1-one
CAS No.:804-20-6
Molecular Formula:C21H18N2O3
Molecular Weight:346.386
Hs Code.:
DSSTox Substance ID:DTXSID901235017
Nikkaji Number:J405.779A

Synonyms:804-20-6;DTXSID901235017;AKOS032958377;3-(4-nitrophenylamino)-1,3-diphenylpropan-1-one;3-[(4-Nitrophenyl)amino]-1,3-diphenyl-1-propanone

Suppliers and Price of 3-(4-Nitrophenylamino)-1,3-diphenylpropan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-(4-Nitrophenylamino)-1,3-diphenylpropan-1-one

Chemical Property:

XLogP3:5.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:346.13174244
Heavy Atom Count:26
Complexity:456

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CC(=O)C2=CC=CC=C2)NC3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 3-(4-Nitrophenylamino)-1,3-diphenylpropan-1-one

There total 5 articles about 3-(4-Nitrophenylamino)-1,3-diphenylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 100-52-7
benzaldehyde

: 100-01-6,104810-17-5
4-nitro-aniline

: 98-86-2
acetophenone

: 804-20-6
1,3-diphenyl-3-[(4-nitrophenyl)amino]propan-1-one

Guidance literature:: With [3-(1-methylimidazolium-3-yl)propane-1-sulfonate]3PW₁₂O₄₀; 1-butyl-3-methylimidazolium trifluoromethanesulfonimide; at 30 ℃; for 20h; Schlenk technique; Sealed tube;
DOI:10.1016/j.tet.2013.10.033

Reference yield: 88.0%

: 100-01-6,104810-17-5
4-nitro-aniline

: 94-41-7
benzalacetophenone

: 804-20-6
1,3-diphenyl-3-[(4-nitrophenyl)amino]propan-1-one

Guidance literature:: In methanol; for 10h; Heating;
DOI:10.1021/je00057a030

Reference yield:

: 100-52-7
benzaldehyde

: 804-20-6
1,3-diphenyl-3-[(4-nitrophenyl)amino]propan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium phosphate / ethanol / 0.25 h / 20 °C

2: ethanol / 1.33 h

With potassium phosphate; In ethanol; 1: |Michael Addition / 2: |Michael Addition;
DOI:10.1007/s00706-012-0729-1