8-(Methylsulfanyl)-9-pentofuranosyl-9h-purin-6-amine

Base Information

Chemical Name:8-(Methylsulfanyl)-9-pentofuranosyl-9h-purin-6-amine
CAS No.:29836-01-9
Molecular Formula:C11H15 N5 O4 S
Molecular Weight:313.337
Hs Code.:
NSC Number:136561
DSSTox Substance ID:DTXSID90952261
Mol file:29836-01-9.mol

Synonyms:8-Methylthioadenosine;29836-01-9;8-(methylsulfanyl)-9-pentofuranosyl-9h-purin-6-amine;NSC136561;DTXSID90952261;2-(6-amino-8-methylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;NSC-136561

Suppliers and Price of 8-(Methylsulfanyl)-9-pentofuranosyl-9h-purin-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of 8-(Methylsulfanyl)-9-pentofuranosyl-9h-purin-6-amine

Chemical Property:

Vapor Pressure:7.93E-21mmHg at 25°C
Boiling Point:704.4°Cat760mmHg
Flash Point:379.8°C
Density:1.98g/cm³
XLogP3:-0.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:3
Exact Mass:313.08447515
Heavy Atom Count:21
Complexity:381

Purity/Quality:: 99.3% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=NC2=C(N=CN=C2N1C3C(C(C(O3)CO)O)O)N

Technology Process of 8-(Methylsulfanyl)-9-pentofuranosyl-9h-purin-6-amine

There total 3 articles about 8-(Methylsulfanyl)-9-pentofuranosyl-9h-purin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 2946-39-6
8-bromoadenosine

: 5188-07-8
sodium thiomethoxide

: 29836-01-9
8-methylsulphanyladenosine

Guidance literature:: In N,N-dimethyl-formamide; for 2h; Ambient temperature;
DOI:10.1055/s-1990-27066

Reference yield:

: 58-61-7
adenosine

: 29836-01-9
8-methylsulphanyladenosine

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / water / 47 h / 20 °C / pH 4 / aq. acetate buffer

2: N,N-dimethyl-formamide / 2 h / 20 °C

With bromine; In water; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2012.04.045