Technology Process of 6-benzylamino-8-methoxycarbonyl-9-(β-D-ribofuranosyl)purine
There total 7 articles about 6-benzylamino-8-methoxycarbonyl-9-(β-D-ribofuranosyl)purine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methanol; 6-benzylamino-8-cyano-9-(β-D-ribofuranosyl)purine;
With
potassium tert-butylate;
at 20 ℃;
for 18h;
With
hydrogenchloride;
In
water;
at -10 ℃;
for 1.5h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: N,N-dimethyl-formamide / 24 h / 50 °C / Molecular sieve
2.1: N,N-dimethyl-formamide / 6 h / 20 °C
3.1: acetic acid; potassium permanganate / 0.75 h / -5 °C
4.1: N,N-dimethyl-formamide / 24 h / 20 °C
5.1: potassium tert-butylate / 18 h / 20 °C
5.2: 1.5 h / -10 °C
With
potassium permanganate; potassium tert-butylate; acetic acid;
In
N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: N,N-dimethyl-formamide / 24 h / 50 °C / Molecular sieve
2.1: acetic acid; potassium permanganate / 0.75 h / -5 °C
3.1: N,N-dimethyl-formamide / 24 h / 20 °C
4.1: potassium tert-butylate / 18 h / 20 °C
4.2: 1.5 h / -10 °C
With
potassium permanganate; potassium tert-butylate; acetic acid;
In
N,N-dimethyl-formamide;
