4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE

Base Information

Chemical Name:4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE
CAS No.:82946-72-3
Molecular Formula:C12H15NO
Molecular Weight:189.257
Hs Code.:2934999090
Mol file:82946-72-3.mol

Synonyms:2-(3-methylphenyl)-4,4-dimethyl-2-oxazoline;4,4-dimethyl-2-(m-tolyl)-4,5-dihydrooxazole;4,4-dimethyl-2-(m-tolyl)-2-oxazoline;

Suppliers and Price of 4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4,4-DIMETHYL-2-(3-METHYLPHENYL)-4,5-DIHYDRO-1,3-OXAZOLE 95.00%
5MG
$ 500.24

Total 3 raw suppliers

Chemical Property of 4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE

Chemical Property:

PSA：21.59000
LogP:1.98600

Purity/Quality:: 4,4-DIMETHYL-2-(3-METHYLPHENYL)-4,5-DIHYDRO-1,3-OXAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE

There total 15 articles about 4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 124-68-5
2-Amino-2-methyl-1-propanol

: 620-23-5
m-tolyl aldehyde

: 82946-72-3
4,4-dimethyl-2-(3-methylphenyl)-2-oxazoline

Guidance literature:: 2-Amino-2-methyl-1-propanol; m-tolyl aldehyde; In dichloromethane; at 25 ℃; for 20h; Inert atmosphere; Schlenk technique; Molecular sieve;

With N-Bromosuccinimide; In dichloromethane; at 25 ℃; for 4h; Inert atmosphere; Schlenk technique; Molecular sieve;
DOI:10.1021/acs.orglett.9b01350

Reference yield: 75.0%

: 30093-99-3
4,4-dimethyl-2-oxazoline

: 591-17-3
meta-bromotoluene

: 82946-72-3
4,4-dimethyl-2-(3-methylphenyl)-2-oxazoline

Guidance literature:: With C₂H₃O₂^(1-)*C₂₀H₃₀OP^(1-)*C₂₀H₃₁OP*Pd⁽²⁺⁾; lithium tert-butoxide; In N,N-dimethyl acetamide; at 100 ℃; for 14h; Inert atmosphere;
DOI:10.1021/ol200986x

Reference yield: 74.0%

: 30093-99-3
4,4-dimethyl-2-oxazoline

: 625-95-6
3-Iodotoluene

: 82946-72-3
4,4-dimethyl-2-(3-methylphenyl)-2-oxazoline

Guidance literature:: With copper(l) iodide; dimethylaminoacetic acid; lithium tert-butoxide; In diethyl ether; at 25 - 27 ℃; for 16h; Inert atmosphere; Sealed tube; Irradiation;
DOI:10.1002/anie.201512027