1-(Chloromethoxy)-2-methylbenzene

Base Information

• Chemical Name: 1-(Chloromethoxy)-2-methylbenzene
• CAS No.: 83142-61-4
• Molecular Formula: C8H9ClO
• Molecular Weight: 156.612
• DSSTox Substance ID: DTXSID00509664
• Wikidata: Q82367414
• Mol file: 83142-61-4.mol

Synonyms:1-(Chloromethoxy)-2-methylbenzene;83142-61-4;2-(Chloromethoxy)toluene;SCHEMBL6205320;DTXSID00509664;MFCD19233064;AKOS006385768;SY298330

Chemical Property of 1-(Chloromethoxy)-2-methylbenzene

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 156.0341926
• Heavy Atom Count: 10
• Complexity: 95.3

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1OCCl

Technology Process of 1-(Chloromethoxy)-2-methylbenzene

There total 1 articles about 1-(Chloromethoxy)-2-methylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

(2-methylphenoxy)acetyl chloride (15516-43-5) → 1-(chloromethoxy)-2-methylbenzene (83142-61-4)

Guidance literature:

With Wilkinson's catalyst; at 160 ℃; for 0.5h;

Reference yield: 86.0%

1-(chloromethoxy)-2-methylbenzene (83142-61-4) + 3-hydroxy-2-methyl-1-propene (513-42-8) → 1-methyl-2-[[(2-methyl-2-propenyl)oxy]methoxy]benzene (690662-35-2)

Guidance literature:

With sodium hydroxide; tetrabutyl-ammonium chloride; In benzene; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2004.01.065

Reference yield: 79.0%

1-(chloromethoxy)-2-methylbenzene (83142-61-4) + allyl alcohol (107-18-6) → 1-methyl-2-[(2-propenyloxy)methoxy]benzene (690662-34-1)

Guidance literature:

With sodium hydroxide; tetrabutyl-ammonium chloride; In benzene; at 20 ℃; for 1.25h;

DOI:10.1016/j.tet.2004.01.065

upstream raw materials:

(2-methylphenoxy)acetyl chloride

Downstream raw materials:

1-(bromomethyl)-2-(chloromethoxy)benzene

1-methyl-2-[(2-propenyloxy)methoxy]benzene

1-methyl-2-[[(2-methyl-2-propenyl)oxy]methoxy]benzene

3-cyclohexyl-3,4-dihydro-2H-benz[e][1,3]oxazine