4,4,5,5-Tetramethyl-2-((Z)-1-propenyl)-1,3,2-dioxaborolane

Base Information

Chemical Name:4,4,5,5-Tetramethyl-2-((Z)-1-propenyl)-1,3,2-dioxaborolane
CAS No.:83947-59-5
Molecular Formula:C9H17BO2
Molecular Weight:168.044
Hs Code.:
Mol file:83947-59-5.mol

Synonyms:4,4,5,5-tetramethyl-2-(prop-1-en-1-yl)-1,3,2-dioxaborolane;4,4,5,5-tetramethyl-2-(2-methyl-vinyl)-1,3,2-dioxaborolane;4,4,5,5-tetramethyl-2-propenyl[1,3,2]dioxaborolane;benzylboronic acid pinacolate ester;4,4,5,5-tetramethyl-2-(phenylmethyl)-1,3,2-dioxaborolane;2-benzyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane;4,4,5,5-tetramethyl-2-(1-propenyl)-1,3,2-dioxaborolane;1-propenylpinacolborane;Benzylboronic acid pinacol est;

Suppliers and Price of 4,4,5,5-Tetramethyl-2-((Z)-1-propenyl)-1,3,2-dioxaborolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
cis-1-PropenylboronicAcidPinacolEster
1g
$ 1320.00

Medical Isotopes, Inc.
cis-1-PropenylboronicAcidPinacolEster
1 g
$ 2200.00

Medical Isotopes, Inc.
cis-1-PropenylboronicAcidPinacolEster
100 mg
$ 650.00

Chemenu
(Z)-4,4,5,5-Tetramethyl-2-(prop-1-en-1-yl)-1,3,2-dioxaborolane 95%mixTBCasstabilizer
1g
$ 282.00

ACHEMBLOCK
(Z)-4,4,5,5-tetramethyl-2-(prop-1-en-1-yl)-1,3,2-dioxaborolane 95%
5G
$ 980.00

ACHEMBLOCK
(Z)-4,4,5,5-tetramethyl-2-(prop-1-en-1-yl)-1,3,2-dioxaborolane 95%
1G
$ 275.00

Total 9 raw suppliers

Chemical Property of 4,4,5,5-Tetramethyl-2-((Z)-1-propenyl)-1,3,2-dioxaborolane

Chemical Property:

Boiling Point:157.2±23.0℃ (760 Torr)
Flash Point:48.9±22.6℃
PSA：18.46000
Density:0.89±0.1 g/cm3 (20 oC 760 Torr)
LogP:2.19390

Purity/Quality:

98%Min ^*data from raw suppliers

cis-1-PropenylboronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 10

MSDS Files:: SDS file from LookChem

Useful:

Uses cis-1-Propenylboronic acid pinacol ester is an substituted alkylboronate that is used in the synthetic preparation of various pharmaceutical goods.

Technology Process of 4,4,5,5-Tetramethyl-2-((Z)-1-propenyl)-1,3,2-dioxaborolane

There total 17 articles about 4,4,5,5-Tetramethyl-2-((Z)-1-propenyl)-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 6386-72-7,6524-17-0,29283-76-9
(E)-propenyl lithium

: 2-(1-bromo-1-methylethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 96041-10-0
pinacol 1-<1,1-dimethyl-2(E)-butenyl>boronate

: 72824-04-5,83947-58-4,83947-59-5,72824-05-6
4,4,5,5-tetramethyl-2-(1-propenyl)-1,3,2-dioxaborolane

Guidance literature:: In diethyl ether; (E)-propenyllithium (6.87 mmol) in Et2O soln. was added dropwise during45 min under Ar to a soln. of 2-bromo-2-propylboronate (6.21 mmol) in Et2O at -78°C;; distn. at 68-70°C (5 mm Hg)gve the product (98% isomerically pure);
DOI:10.1021/ja00272a043

Reference yield: 78.0%

: 76-09-5
2,3-dimethyl-2,3-butane diol

: 590-13-6
(Z)-1-propenyl bromide

: 83947-59-5
(Z)-4,4,5,5-tetramethyl-2-(prop-1-en-1-yl)-1,3,2-dioxaborolane

Guidance literature:: (Z)-1-propenyl bromide; With tert.-butyl lithium; In diethyl ether; pentane; at -98 ℃; for 0.25h;

With Trimethyl borate; In diethyl ether; pentane; at -98 - 0 ℃;

2,3-dimethyl-2,3-butane diol; With magnesium sulfate; at 0 ℃;
DOI:10.1021/ja044878s

Reference yield: 65.0%

: 917-54-4
methyllithium

: (Z)-2-(2-bromovinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 83947-59-5
(Z)-4,4,5,5-tetramethyl-2-(prop-1-en-1-yl)-1,3,2-dioxaborolane

Guidance literature:: methyllithium; With zinc(II) chloride; In diethyl ether; at -78 - 20 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

(Z)-2-(2-bromovinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; diethyl ether; at 20 ℃; for 2h; Inert atmosphere; Schlenk technique; Darkness;
DOI:10.1021/acs.joc.0c00341