Ethyl 2,4-dimethyl-1,3-dioxolane-2-acetate

Base Information

Chemical Name:Ethyl 2,4-dimethyl-1,3-dioxolane-2-acetate
CAS No.:6290-17-1
Deprecated CAS:948854-83-9
Molecular Formula:C9H16O4
Molecular Weight:188.224
Hs Code.:2932999099
European Community (EC) Number:228-536-2
NSC Number:6547
DSSTox Substance ID:DTXSID4047549
Nikkaji Number:J37.791K
Metabolomics Workbench ID:45323
ChEMBL ID:CHEMBL3183430
Mol file:6290-17-1.mol

Synonyms:6290-17-1;ethyl 2-(2,4-dimethyl-1,3-dioxolan-2-yl)acetate;Ethyl acetoacetate propylene glycol ketal;Ethyl 2,4-dimethyl-1,3-dioxolane-2-acetate;1,3-Dioxolane-2-acetic acid, 2,4-dimethyl-, ethyl ester;Fraistone;cis- and trans-Ethyl 2,4-dimethyl-1,3-dioxolane-2-acetate;DTXSID4047549;UNII-087792Q4F6;NSC 6547;Acetoacetic acid, ethyl ester, 1,2-propylene ketal;EINECS 228-536-2;ethyl (2,4-dimethyl-1,3-dioxolan-2-yl)acetate;fruity ketal;Ethyl dimethyl dioxolane acetate;SCHEMBL528798;CHEMBL3183430;DTXCID2027549;Ethyl 2,3-dioxolane-2-acetate;NSC6547;CHEBI:173896;NSC-6547;Tox21_302457;LMFA07010803;MFCD00151819;STK096389;AKOS005395944;ethyl 2,4-dimethyldioxolane-2-acetate;Ethyl actoacetate propyleneglycol ketal;Acetoacetic acid, 1,2-propylene ketal;CS-W016805;Ethyl acetoacetate propyleneglycol ketal;NCGC00256795-01;BS-17275;CAS-6290-17-1;087792Q4F6;E1417;FT-0621774;E75757;Ethyl 2, 4-dimethyl-1,3-dioxolane-2-acetate;ethyl2-(2,4-dimethyl-1,3-dioxolan-2-yl)acetate;2,4-Dimethyl-1,3-dioxolane-2-acetic acid ethyl ester;ethyl 2,4 - dimethyl - 1,3 - dioxolane - 2 - acetate

Suppliers and Price of Ethyl 2,4-dimethyl-1,3-dioxolane-2-acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
Ethyl 2-(2,4-Dimethyl-1,3-dioxolan-2-yl)acetate (mixture of diastereoisomers)
100G
$ 110.00

TCI Chemical
Ethyl 2-(2,4-Dimethyl-1,3-dioxolan-2-yl)acetate (mixture of diastereoisomers)
25G
$ 38.00

SynQuest Laboratories
Ethylacetoacetatepropyleneglycolketal 98.0%
100 g
$ 168.00

Sigma-Aldrich
Ethyl dimethyl dioxolane acetate mixture of isomers, ≥97%, FG
1 kg
$ 250.00

Sigma-Aldrich
Ethyl dimethyl dioxolane acetate mixture of isomers, ≥97%, FG
1kg-k
$ 250.00

Sigma-Aldrich
Ethyl dimethyl dioxolane acetate mixtureofisomers,≥97%,FG
1 SAMPLE-K
$ 50.00

Sigma-Aldrich
Ethyl dimethyl dioxolane acetate mixture of isomers, ≥97%, FG
sample-k
$ 50.00

Sigma-Aldrich
Ethyl dimethyl dioxolane acetate mixture of isomers, ≥97%, FG
100 g
$ 31.00

Sigma-Aldrich
Ethyl dimethyl dioxolane acetate mixture of isomers, ≥97%, FG
100g-k
$ 30.00

Alfa Aesar
Ethyl acetoacetate propylene glycol ketal, 97%
100g
$ 113.00

Total 29 raw suppliers

Chemical Property of Ethyl 2,4-dimethyl-1,3-dioxolane-2-acetate

Chemical Property:

Appearance/Colour:colourless to pale yellow liquid
Vapor Pressure:0.112mmHg at 25°C
Refractive Index:1.4280
Boiling Point:220.6 °C at 760 mmHg
Flash Point:86.8 °C
PSA：44.76000
Density:1.026 g/cm³
LogP:1.09110
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Water Solubility.:1.244g/L at 24℃
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:188.10485899
Heavy Atom Count:13
Complexity:192

Purity/Quality:

99.9% ^*data from raw suppliers

Ethyl 2-(2,4-Dimethyl-1,3-dioxolan-2-yl)acetate (mixture of diastereoisomers) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25-23

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1(OCC(O1)C)C

Technology Process of Ethyl 2,4-dimethyl-1,3-dioxolane-2-acetate

There total 2 articles about Ethyl 2,4-dimethyl-1,3-dioxolane-2-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 57-55-6,63625-56-9
propylene glycol

: 141-97-9
ethyl acetoacetate

: 6290-17-1
ethyl 2-(2,4-dimethyl-1,3-dioxolan-2-yl)acetate

Guidance literature:: With Amberlyst₁₅; In cyclohexane; Reflux;

Reference yield:

: 6290-17-1
ethyl 2-(2,4-dimethyl-1,3-dioxolan-2-yl)acetate

Guidance literature:: Acetessigsaeure-aethylester, Propandiol-(1,2), p-Toluolsulfonsaeure, Toluol, Siedetemp.;
DOI:10.1021/jo01075a009

Reference yield:

: 6290-17-1
ethyl 2-(2,4-dimethyl-1,3-dioxolan-2-yl)acetate

: 2243-58-5
2-naphthylhydrazine hydrochloride

: 1192140-15-0
5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-ol

: 1357362-21-0
3-methyl-1-(naphthalen-2-yl)-1H-pyrazol-5-ol

Guidance literature:: ethyl 2-(2,4-dimethyl-1,3-dioxolan-2-yl)acetate; 2-naphthylhydrazine hydrochloride; With sodium methylate; In toluene; at 80 - 85 ℃; for 4.5h;

With hydrogenchloride; water; In methanol; for 1.5h; Reflux;

With sodium hydroxide; In methanol; dichloromethane; water; pH=12.2 - 12.7;