N,N'-bis(4-ethoxyphenyl)propanediamide

Base Information

Chemical Name:N,N'-bis(4-ethoxyphenyl)propanediamide
CAS No.:4270-37-5
Molecular Formula:C19H22N2O4
Molecular Weight:342.395
Hs Code.:2924299090
DSSTox Substance ID:DTXSID40367922
Wikidata:Q82154109
ChEMBL ID:CHEMBL1608714
Mol file:4270-37-5.mol

Synonyms:N,N'-bis(4-ethoxyphenyl)propanediamide;4270-37-5;N,N'-Bis-(4-ethoxy-phenyl)-malonamide;N,N''-BIS-(4-ETHOXY-PHENYL)-MALONAMIDE;Oprea1_377760;MLS001175132;SCHEMBL9312707;CHEMBL1608714;DTXSID40367922;HMS1784B01;HMS2875H08;n1,n3-Bis(4-ethoxyphenyl)malonamide;STK877398;AKOS000115204;SMR000588406;CS-0299410;EN300-01426;AB00710449-01

Suppliers and Price of N,N'-bis(4-ethoxyphenyl)propanediamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N,N'-BIS-(4-ETHOXY-PHENYL)-MALONAMIDE 95.00%
5G
$ 1005.43

American Custom Chemicals Corporation
N,N'-BIS-(4-ETHOXY-PHENYL)-MALONAMIDE 95.00%
2.5G
$ 852.21

American Custom Chemicals Corporation
N,N'-BIS-(4-ETHOXY-PHENYL)-MALONAMIDE 95.00%
1G
$ 648.81

Total 1 raw suppliers

Chemical Property of N,N'-bis(4-ethoxyphenyl)propanediamide

Chemical Property:

Boiling Point:617.7°Cat760mmHg
Flash Point:327.4°C
PSA：76.66000
Density:1.218g/cm³
LogP:3.59730
XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:342.15795719
Heavy Atom Count:25
Complexity:376

Purity/Quality:

99% ^*data from raw suppliers

N,N'-BIS-(4-ETHOXY-PHENYL)-MALONAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC=C(C=C1)NC(=O)CC(=O)NC2=CC=C(C=C2)OCC

Technology Process of N,N'-bis(4-ethoxyphenyl)propanediamide

There total 6 articles about N,N'-bis(4-ethoxyphenyl)propanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 4270-39-7
4-ethoxymalonanilic acid ethyl ester

: 4270-37-5
N,N'-di-4-ethoxyanilide of malonic acid

: 105-53-3
diethyl malonate

Guidance literature:: In N,N-dimethyl-formamide; for 5h; Heating;
DOI:10.1016/S0040-4020(01)81765-8

Reference yield:

: 156-43-4
4-Ethoxyaniline

: 4270-37-5
N,N'-di-4-ethoxyanilide of malonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / Et₃N / acetone / Ambient temperature

2: 97 percent / dimethylformamide / 5 h / Heating

With triethylamine; In N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)81765-8

Reference yield:

: 10378-80-0
N,N'-bis-(4-hydroxy-phenyl)-malonamide

: 75-03-6
ethyl iodide

: 4270-37-5
N,N'-di-4-ethoxyanilide of malonic acid

Guidance literature:: With potassium hydroxide; ethanol; zur Trennung loest man das Gemisch in warmem Alkohol; beim Abkuehlen scheidet sich zunaechst Malonsaeure-di-p-phenetidid aus;