6-Amino-5-nitropyridine-2-carboxylic acid

Base Information

Chemical Name:6-Amino-5-nitropyridine-2-carboxylic acid
CAS No.:84487-06-9
Molecular Formula:C₆H₅N₃O₄
Molecular Weight:183.123
Hs Code.:
DSSTox Substance ID:DTXSID50704627
Wikidata:Q82637101
Mol file:84487-06-9.mol

Synonyms:6-Amino-5-nitropyridine-2-carboxylic acid;84487-06-9;6-Amino-5-nitropicolinic acid;SCHEMBL23753908;DTXSID50704627;AKOS023398088;6-Amino-5-nitropyridine-2-carboxylicacid;CS-0371941;FT-0703980;EN300-127274

Suppliers and Price of 6-Amino-5-nitropyridine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-amino-5-nitropyridine-2-carboxylicacid
50mg
$ 220.00

Chemcia Scientific
6-Amino-5-nitro-pyridine-2-carboxylicacid 95%
1 G
$ 550.00

AK Scientific
6-Amino-5-nitropyridine-2-carboxylicacid
2.5g
$ 1913.00

Total 4 raw suppliers

Chemical Property of 6-Amino-5-nitropyridine-2-carboxylic acid

Chemical Property:

PSA：122.03000
LogP:1.37460
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:183.02800565
Heavy Atom Count:13
Complexity:226

Purity/Quality:

97% ^*data from raw suppliers

6-amino-5-nitropyridine-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC(=C1[N+](=O)[O-])N)C(=O)O

Technology Process of 6-Amino-5-nitropyridine-2-carboxylic acid

There total 4 articles about 6-Amino-5-nitropyridine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 353277-27-7
6-chloro-5-nitropyridine-2-carboxylic acid

: 84487-06-9
6-amino-5-nitropyridine-2-carboxylic acid

Guidance literature:: With ammonium hydroxide; In tetrahydrofuran; at 50 ℃;

Reference yield:

: 2-amino-6-(2-(dimethylamino)vinyl)-3-nitropyridine

: 84487-06-9
6-amino-5-nitropyridine-2-carboxylic acid

Guidance literature:: 2-amino-6-(2-(dimethylamino)vinyl)-3-nitropyridine; In tert-butyl alcohol; for 0.5h; Sonication;

With potassium permanganate; potassium carbonate; In water; tert-butyl alcohol; at 20 ℃; for 6h;
DOI:10.1021/acs.orglett.6b02359

Reference yield:

: 21901-29-1
6-amino-5-nitro-2-picoline

: 84487-06-9
6-amino-5-nitropyridine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 38.5 percent / dimethylformamide / 16 h / 140 °C

2: 1.8 g / potassium carbonate; potassium permanganate / H₂O; 2-methyl-propan-2-ol / 3 h

With potassium permanganate; potassium carbonate; In water; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1016/j.bmc.2005.01.042