2,5-Dimethoxy-4-(4-nitrophenylazo)aniline

Base Information

• Chemical Name: 2,5-Dimethoxy-4-(4-nitrophenylazo)aniline
• CAS No.: 6358-51-6
• Molecular Formula: C14H14 N4 O4
• Molecular Weight: 302.29
• Hs Code.: 2927000090
• European Community (EC) Number: 228-777-3
• DSSTox Substance ID: DTXSID001039064
• Nikkaji Number: J37.811I
• Mol file: 6358-51-6.mol

Synonyms:6358-51-6;2,5-Dimethoxy-4-(4-nitrophenylazo)aniline;2,5-dimethoxy-4-[(4-nitrophenyl)diazenyl]aniline;EINECS 228-777-3;Benzenamine, 2,5-dimethoxy-4-[(4-nitrophenyl)azo]-;(E)-2,5-Dimethoxy-4-((4-nitrophenyl)diazenyl)aniline;1256781-52-8;Benzenamine, 2,5-dimethoxy-4-((4-nitrophenyl)azo)-;C.I. Disperse Blue 11;SCHEMBL716594;SCHEMBL14704208;DTXSID001039064;4-amino-2,5-dimethoxy-4'-nitroazobenzene;C.I.11260;2,5-Dimethoxy-4-(4-nitrophenyl)diazenylaniline;W-110109;1-[(4-amino-2,5-dimethoxyphenyl) diazenyl]-4-nitrobenzene;Benzenamine, 2,5-dimethoxy-4-[2-(4-nitrophenyl)diazenyl]-

Chemical Property of 2,5-Dimethoxy-4-(4-nitrophenylazo)aniline

Chemical Property:

• Vapor Pressure: 1.64E-11mmHg at 25°C
• Boiling Point: 534.8°C at 760 mmHg
• Flash Point: 277.2°C
• PSA: 115.02000
• Density: 1.35g/cm³
• LogP: 4.71400
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 302.10150494
• Heavy Atom Count: 22
• Complexity: 393

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1N)OC)N=NC2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 2,5-Dimethoxy-4-(4-nitrophenylazo)aniline

There total 4 articles about 2,5-Dimethoxy-4-(4-nitrophenylazo)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-nitro-aniline (100-01-6,104810-17-5) + 2,5-dimethoxyaniline (102-56-7,102526-87-4) → (E)-2,5-dimethoxy-4-((4-nitrophenyl)diazenyl)aniline (6358-51-6)

Guidance literature:

4-nitro-aniline; With hydrogenchloride; sodium nitrite; In methanol; water; at 0 ℃;

2,5-dimethoxyaniline; With hydrogenchloride; In methanol; water; at 0 ℃;

With sodium acetate; In methanol; water; pH=4;

DOI:10.1002/asia.200900386

Reference yield:

4-nitro-aniline (100-01-6,104810-17-5) → (E)-2,5-dimethoxy-4-((4-nitrophenyl)diazenyl)aniline (6358-51-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid; nitrosylhydrogen sulfate / beim Eintragen der Reaktionsloesung in eine Suspension von Essigsaeure-<2.5-dimethoxy-anilid> in Methanol

With nitrosylsulfuric acid; sulfuric acid;

Reference yield:

acetic acid-[2,5-dimethoxy-4-(4-nitro-phenylazo)-anilide] → (E)-2,5-dimethoxy-4-((4-nitrophenyl)diazenyl)aniline (6358-51-6)

Guidance literature:

upstream raw materials:

4-nitro-aniline

2,5-dimethoxyaniline

4-nitrobenzenediazonium chloride

Downstream raw materials:

2-((4-((E)-(2,5-dimethoxy-4-((E)-(4-nitrophenyl)diazenyl)phenyl)diazenyl)phenyl)(methyl)amino)ethanol

Fast Black K salt