Glycine, N-dodecyl-

Base Information

• Chemical Name: Glycine, N-dodecyl-
• CAS No.: 2274-80-8
• Molecular Formula: C14H29 N O2
• Molecular Weight: 243.39
• Hs Code.: 2922499990
• NSC Number: 18494
• DSSTox Substance ID: DTXSID00177281
• Nikkaji Number: J127.634D
• Mol file: 2274-80-8.mol

Synonyms:GLYCINE, N-DODECYL-;Dodecylglycine;2274-80-8;2-(dodecylamino)acetic acid;N-Laurylaminoacetic acid;N-Dodecylglycine;NSC 18494;BRN 1778706;4-04-00-02386 (Beilstein Handbook Reference);Armac-C;N-Dodecyl-glycine;N-n-dodecylglycine;SCHEMBL410583;DTXSID00177281;NSC18494;NSC-18494;AKOS011342012;LS-72618;F79883

Chemical Property of Glycine, N-dodecyl-

Chemical Property:

• Vapor Pressure: 4.83E-06mmHg at 25°C
• Boiling Point: 356.4°Cat760mmHg
• Flash Point: 169.4°C
• PSA: 49.33000
• Density: 0.925g/cm³
• LogP: 3.97240
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 13
• Exact Mass: 243.219829168
• Heavy Atom Count: 17
• Complexity: 172

Purity/Quality:

99%min ^*data from raw suppliers

N-LAURYLAMINOACETIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCNCC(=O)O

Technology Process of Glycine, N-dodecyl-

There total 9 articles about Glycine, N-dodecyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

n-Dodecylamine (124-22-1) + Iodoacetic acid (64-69-7) → 2-(dodecylamino)acetic acid (2274-80-8)

Guidance literature:

In ethanol; water; at 0 - 20 ℃; for 20h;

DOI:10.1021/ja101937w

Reference yield: 53.5%

Dodecylglycine nitrile (6291-94-7) → 2-(dodecylamino)acetic acid (2274-80-8)

Guidance literature:

With sulfuric acid; at 120 - 130 ℃; for 3h;

DOI:10.1007/BF00759466

Reference yield:

1-dodecyl alcohol (112-53-8) + glycine (56-40-6,18875-39-3,25718-94-9) → 2-(dodecylamino)acetic acid (2274-80-8) + N,N-di-n-dodecylglycine (65527-68-6)

Guidance literature:

With 2,2,2-trifluoroethanol; dicarbonyl-(2,4-bis(trimethylsilyl)bicyclo[3.3.0]nona-1,4-dien-3-one)[acetonitrile]iron; at 110 ℃; for 24h; Schlenk technique; Inert atmosphere;

upstream raw materials:

formaldehyd

n-Dodecylamine

sodium cyanide

sodium monochloroacetic acid

Downstream raw materials:

C₁₁₂H₆₉N₇O₄

C₆₀C₂H₃N((CH₂)11Me)C₆H₄CCC₆H₃(C(O)NHC₅H₃NNHC(O)CH₂CMe₃)2

C₈₈H₄₉N

C₆₀-fused N-dodecyl-2-(4-nonafluorobutyl)phenylpyrrolidine

Refernces

• 1、 -. "N-ALKYLATED AMINO ACIDS AND OLIGOPEPTIDES, USES THEREOF AND METHODS FOR PROVIDING THEM.". Page/Page column 17-19; 34-36; 47. . Retrieved 2018/10/25.
• 2、 Limanov, V. E.,Ivanov, S. B.,Sukiasyan, A. N.,Skvortsova, E. K.. "SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF COMPOUNDS OBTAINED FROM HIGHER ALKYLAMINES". . p. 383 - 387. Retrieved 2007/10/02.