(2-Hydroxypropyl)triphenylphosphonium bromide

Base Information

• Chemical Name: (2-Hydroxypropyl)triphenylphosphonium bromide
• CAS No.: 3020-30-2
• Molecular Formula: C21H22 O P . Br
• Molecular Weight: 401.283
• NSC Number: 110605
• Mol file: 3020-30-2.mol

Synonyms:NSC110605;(2-Hydroxypropyl)triphenylphosphonium bromide;AKOS024322395;NSC-110605;(2-Hydroxypropyl)triphenylphosphoniumbromide

Chemical Property of (2-Hydroxypropyl)triphenylphosphonium bromide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 400.05916
• Heavy Atom Count: 24
• Complexity: 292

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)O.[Br-]

Technology Process of (2-Hydroxypropyl)triphenylphosphonium bromide

There total 4 articles about (2-Hydroxypropyl)triphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

4-methyl-2-phenyl-1,3-dioxolane (2568-25-4) + triphenylphosphine hydrobromide (6399-81-1) → (2-hydroxypropyl)triphenylphosphonium bromide (3020-30-2) + benzaldehyde (100-52-7)

Guidance literature:

In dichloromethane; at 50 ℃; for 0.0833333h; Microwave irradiation; Sealed tube;

DOI:10.3998/ark.5550190.0014.308

Reference yield:

triphenylphosphine (603-35-0) + methyloxirane (75-56-9,16033-71-9) → Methyltriphenylphosphonium bromide (1779-49-3) + (2-hydroxypropyl)triphenylphosphonium bromide (3020-30-2) + (E)-prop-1-en-1-yl-triphenylphosphonium bromide (28691-76-1)

Guidance literature:

Product distribution; multistep reaction; variation of temperature and reaction time;

Reference yield:

triphenylphosphine (603-35-0) + methyloxirane (75-56-9,16033-71-9) → (2-hydroxypropyl)triphenylphosphonium bromide (3020-30-2)

Guidance literature:

With hydrogen bromide; phenol; Yield given. Multistep reaction; 1.) 60 deg C, 4 h;

upstream raw materials:

allyltriphenylphosphonium bromide

triphenylphosphine

methyloxirane

4-methyl-2-phenyl-1,3-dioxolane

Refernces

• 1、 Shibata, Ikuya,Mitani, Ikuko,Imakuni, Akira,Baba, Akio. "Highly efficient synthesis of cyclic carbonates from epoxides catalyzed by indium tribromide system". experimental part. p. 721 - 723. Retrieved 2011/03/20.