2-methoxy-4-(trifluoromethoxy)benzoic Acid

Base Information

Chemical Name:2-methoxy-4-(trifluoromethoxy)benzoic Acid
CAS No.:848947-91-1
Molecular Formula:C9H7F3O4
Molecular Weight:236.147
Hs Code.:2918990090
European Community (EC) Number:889-805-3
Mol file:848947-91-1.mol

Synonyms:2-methoxy-4-(trifluoromethoxy)benzoic Acid;848947-91-1;Benzoic acid, 2-methoxy-4-(trifluoromethoxy)-;2-Methoxy-4-trifluoromethoxy-benzoic acid;SCHEMBL1972074;YIB94791;MFCD04115966;AKOS015956993;JS-4307;2-methoxy-4-(trifluoromethoxy)benzoicAcid;2-methoxy-4-(trifluoromethoxy)-benzoic acid;CS-0317109;EN300-11690047;Z2044764966

Suppliers and Price of 2-methoxy-4-(trifluoromethoxy)benzoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Methoxy-4-(trifluoromethoxy)benzoic acid
1 g
$ 45.00

Matrix Scientific
2-Methoxy-4-(trifluoromethoxy)benzoic acid
25g
$ 515.00

Matrix Scientific
2-Methoxy-4-(trifluoromethoxy)benzoic acid
5g
$ 130.00

Crysdot
2-Methoxy-4-(trifluoromethoxy)benzoicacid 95+%
25g
$ 433.00

Alichem
2-Methoxy-4-(trifluoromethoxy)benzoicacid
1g
$ 1519.80

Alichem
2-Methoxy-4-(trifluoromethoxy)benzoicacid
500mg
$ 815.00

Alichem
2-Methoxy-4-(trifluoromethoxy)benzoicacid
250mg
$ 504.00

Alfa Aesar
2-Methoxy-4-(trifluoromethoxy)benzoic acid, 97%
10g
$ 268.00

Alfa Aesar
2-Methoxy-4-(trifluoromethoxy)benzoic acid, 97%
1g
$ 48.70

Total 5 raw suppliers

Chemical Property of 2-methoxy-4-(trifluoromethoxy)benzoic Acid

Chemical Property:

Melting Point:87-89℃
PSA：55.76000
LogP:2.29200
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:236.02964319
Heavy Atom Count:16
Complexity:254

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

2-Methoxy-4-(trifluoromethoxy)benzoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)OC(F)(F)F)C(=O)O

Technology Process of 2-methoxy-4-(trifluoromethoxy)benzoic Acid

There total 3 articles about 2-methoxy-4-(trifluoromethoxy)benzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 848360-85-0
1-bromo-2-methoxy-4-(trifluoromethoxy)benzene

: 124-38-9,18923-20-1
carbon dioxide

: 848947-91-1
2-methoxy-4-(trifluoromethoxy)-benzoic acid

Guidance literature:: 1-bromo-2-methoxy-4-(trifluoromethoxy)benzene; With n-butyllithium; In hexanes; diethyl ether; at -78 ℃; for 0.333333h;

carbon dioxide; In hexanes; diethyl ether; at -78 - 20 ℃;

Reference yield:

: 205371-26-2
2-bromo-5-(trifluoromethyloxy)phenol

: 848947-91-1
2-methoxy-4-(trifluoromethoxy)-benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / water; toluene / 0.33 h / 1 - 10 °C

1.2: 12 - 15 °C

2.1: n-butyllithium / hexanes; diethyl ether / 0.33 h / -78 °C

2.2: -78 - 20 °C

With sodium hydroxide; n-butyllithium; In hexanes; diethyl ether; water; toluene;

Reference yield:

: 827-99-6
3-(trifluoromethoxy)phenol

: 848947-91-1
2-methoxy-4-(trifluoromethoxy)-benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: bromine / dichloromethane / 2 h / 5 - 10 °C

2.1: sodium hydroxide / water; toluene / 0.33 h / 1 - 10 °C

2.2: 12 - 15 °C

3.1: n-butyllithium / hexanes; diethyl ether / 0.33 h / -78 °C

3.2: -78 - 20 °C

With sodium hydroxide; n-butyllithium; bromine; In hexanes; diethyl ether; dichloromethane; water; toluene;