Propanoic acid, 3,3'-[[2-[[3-oxo-3-(pentachlorophenoxy)propoxy]methyl]-2-[[(phenylmeth oxy)carbonyl]amino]-1,3-propanediyl]bis(oxy)]bis-, bis(pentachlorophenyl) ester

Base Information

• Chemical Name: Propanoic acid, 3,3'-[[2-[[3-oxo-3-(pentachlorophenoxy)propoxy]methyl]-2-[[(phenylmeth oxy)carbonyl]amino]-1,3-propanediyl]bis(oxy)]bis-, bis(pentachlorophenyl) ester
• CAS No.: 849114-67-6
• Molecular Formula: C39H26Cl15NO11
• Molecular Weight: 1216.43
• Mol file: 849114-67-6.mol

Synonyms:

Chemical Property of Propanoic acid, 3,3'-[[2-[[3-oxo-3-(pentachlorophenoxy)propoxy]methyl]-2-[[(phenylmeth oxy)carbonyl]amino]-1,3-propanediyl]bis(oxy)]bis-, bis(pentachlorophenyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Propanoic acid, 3,3'-[[2-[[3-oxo-3-(pentachlorophenoxy)propoxy]methyl]-2-[[(phenylmeth oxy)carbonyl]amino]-1,3-propanediyl]bis(oxy)]bis-, bis(pentachlorophenyl) ester

There total 4 articles about Propanoic acid, 3,3'-[[2-[[3-oxo-3-(pentachlorophenoxy)propoxy]methyl]-2-[[(phenylmeth oxy)carbonyl]amino]-1,3-propanediyl]bis(oxy)]bis-, bis(pentachlorophenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

Pentachlorophenol (87-86-5,67471-28-7) + benzyl N-tris[(2-carboxyethyloxy)methyl]methylcarbamate (200133-16-0) → benzyl N-tris{[2-(2,3,4,5,6-pentachlorophenoxycarbonyl)ethoxy]methyl}methyl carbamate (849114-67-6)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃; for 48h;

DOI:10.1016/j.bmc.2004.11.053

Reference yield:

benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate (220431-66-3) → benzyl N-tris{[2-(2,3,4,5,6-pentachlorophenoxycarbonyl)ethoxy]methyl}methyl carbamate (849114-67-6)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOH / ethanol; H₂O / 0 °C

2: 72 percent / 4-(dimethylamino)pyridine; DCC / tetrahydrofuran / 48 h / 20 °C

With dmap; sodium hydroxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; ethanol; water;

DOI:10.1016/j.bmc.2004.11.053

Reference yield:

3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester (132491-90-8) → benzyl N-tris{[2-(2,3,4,5,6-pentachlorophenoxycarbonyl)ethoxy]methyl}methyl carbamate (849114-67-6)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / dioxane

2: NaOH / ethanol; H₂O / 0 °C

3: 72 percent / 4-(dimethylamino)pyridine; DCC / tetrahydrofuran / 48 h / 20 °C

With dmap; sodium hydroxide; potassium carbonate; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,4-dioxane; ethanol; water;

DOI:10.1016/j.bmc.2004.11.053

upstream raw materials:

Pentachlorophenol

benzyl N-tris[(2-carboxyethyloxy)methyl]methylcarbamate

benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate

3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester

Downstream raw materials:

benzyl N-tris{[2-[((N-hydroxy-N-methylcarbamoyl)methyl)aminocarbonyl]ethoxy]methyl}methylcarbamate