benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate

Base Information

• Chemical Name: benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate
• CAS No.: 220431-66-3
• Molecular Formula: C₂₇H₄₁NO₁₁
• Molecular Weight: 555.623
• Mol file: 220431-66-3.mol

Synonyms:benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate

Chemical Property of benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate

There total 5 articles about benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethanol (64-17-5) + benzyl N-tris[(2-carboxyethyloxy)methyl]methylcarbamate (200133-16-0) → benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate (220431-66-3)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; Heating;

DOI:10.1021/ma0498215

Reference yield: 89.0%

3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester (132491-90-8) + benzyl chloroformate (501-53-1,94274-21-2) → benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate (220431-66-3)

Guidance literature:

With sodium carbonate; In 1,4-dioxane; water; for 12h;

DOI:10.1021/ja021203l

Reference yield:

tris(cyanoethoxymethyl)aminomethane (132491-89-5) → benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate (220431-66-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄ / Heating

2: K₂CO₃ / dioxane

With sulfuric acid; potassium carbonate; In 1,4-dioxane;

DOI:10.1016/j.bmc.2004.11.053

upstream raw materials:

ethanol

benzyl N-tris[(2-carboxyethyloxy)methyl]methylcarbamate

3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester

benzyl chloroformate

Downstream raw materials:

C₃₀H₅₃N₇O₈

3-[2-(benzyloxycarbonylamino)-3-(2-carboxyethoxy)-2-(2-carboxyethoxymethyl)-propoxy]propanoic acid

C₆₃H₉₈N₁₀O₂₀

benzyl N-tris{[2-[((N-hydroxy-N-methylcarbamoyl)methyl)aminocarbonyl]ethoxy]methyl}methylcarbamate