3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester

Base Information

• Chemical Name: 3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester
• CAS No.: 132491-90-8
• Molecular Formula: C₁₉H₃₅NO₉
• Molecular Weight: 421.488
• Mol file: 132491-90-8.mol

Synonyms:3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester

Chemical Property of 3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester

There total 7 articles about 3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate (220431-66-3) → 3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester (132491-90-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃;

DOI:10.1021/ma0498215

Reference yield: 74.0%

ethanol (64-17-5) + tris(cyanoethoxymethyl)aminomethane (132491-89-5) → 3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester (132491-90-8)

Guidance literature:

With hydrogenchloride; for 6h; Heating / reflux;

Reference yield: 51.0%

ethanol (64-17-5) + acrylonitrile (107-13-1,25014-41-9) + 2-amino-2-hydroxymethyl-1,3-propanediol (77-86-1) → 3-[2-Amino-3-(2-ethoxycarbonyl-ethoxy)-2-(2-ethoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid ethyl ester (132491-90-8)

Guidance literature:

acrylonitrile; 2-amino-2-hydroxymethyl-1,3-propanediol; With water; sodium hydroxide;

ethanol; With hydrogenchloride; water;

DOI:10.1039/c0ob00372g

upstream raw materials:

ethanol

tris(cyanoethoxymethyl)aminomethane

benzyl N-{tris[2-(ethoxycarbonyl)ethoxymethyl]methyl}carbamate

tris{[2-(tert-butoxycarbonyl)ethoxy]methyl}methylamine

Downstream raw materials:

C₃₀H₅₃N₇O₈

3-[2-(benzyloxycarbonylamino)-3-(2-carboxyethoxy)-2-(2-carboxyethoxymethyl)-propoxy]propanoic acid

C₃₇H₂₆F₁₅NO₁₀

[3-(3-{2-(2-benzyloxycarbonylamino-acetylamino)-3-[2-(3-tert-butoxycarbonylamino-propylcarbamoyl)-ethoxy]-2-[2-(3-tert-butoxycarbonylamino-propylcarbamoyl)-ethoxymethyl]-propoxy}-propionylamino)-propyl]-carbamic acid tert-butyl ester