Guaijaverin

Base Information

Chemical Name:Guaijaverin
CAS No.:22255-13-6
Molecular Formula:C₂₀H₁₈O₁₁
Molecular Weight:434.356
Hs Code.:
European Community (EC) Number:250-156-0
DSSTox Substance ID:DTXSID60176795
Nikkaji Number:J94.528E
Wikipedia:Guaijaverin
Metabolomics Workbench ID:136576
ChEMBL ID:CHEMBL464507
Mol file:22255-13-6.mol

Synonyms:guajavarin;quercetin 3-O-alpha-L-arabinoside

Suppliers and Price of Guaijaverin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Quercetin 3-O-alpha-L-Arabinopyranoside
10mg
$ 490.00

TRC
Quercetin 3-O-α-L-arabinopyranoside
1mg
$ 105.00

Sigma-Aldrich
Quercetin 3-O-α-L-arabinopyranoside analytical standard
5mg
$ 501.00

Sigma-Aldrich
Quercetin 3-O-α-L-arabinopyranoside ≥95% (HPLC)
1mg
$ 380.00

Sigma-Aldrich
Guaiaverin phyproof? Reference Substance
10mg
$ 207.00

CSNpharm
Guaijaverin
5mg
$ 100.00

Crysdot
Guaijaverin 95+%
10mg
$ 150.00

Crysdot
Guaijaverin 95+%
5mg
$ 100.00

ChemScene
Guaijaverin
5mg
$ 235.00

ChemScene
Guaijaverin
10mg
$ 400.00

Total 57 raw suppliers

Chemical Property of Guaijaverin

Chemical Property:

Melting Point:237-239 °C
Boiling Point:828.061 °C at 760 mmHg
PKA:6.17±0.40(Predicted)
Flash Point:296.325 °C
PSA：190.28000
Density:1.863 g/cm³
LogP:0.10020
Storage Temp.:room temp
Solubility.:DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
XLogP3:0.4
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:3
Exact Mass:434.08491139
Heavy Atom Count:31
Complexity:711

Purity/Quality:

99% ^*data from raw suppliers

Quercetin 3-O-alpha-L-Arabinopyranoside ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)O)O)O)O)O
Isomeric SMILES:C1[C@@H]([C@@H]([C@H]([C@@H](O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)O)O)O)O)O
Uses Quercetin 3-O-α-L-Arabinopyranoside is a derivative of Quercetin (Q509500), a flavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

Technology Process of Guaijaverin

There total 4 articles about Guaijaverin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 117-39-5,74893-81-5
quercetol

: 21401-20-7,30329-30-7,38-57-3,97905-92-5,7164-64-9
C₁₄H₂₂N₂O₁₆P₂

: 6743-88-0,22255-13-6,72581-59-0,94131-44-9
quercetin 3-O-L-arabinopyranoside

Guidance literature:: With 3-O-glycosyltransferase from Scutellaria baicalensis; In aq. buffer; at 45 ℃; for 1h; pH=9; regiospecific reaction; Enzymatic reaction;
DOI:10.1021/acs.orglett.9b00524

Reference yield:

: 357194-03-7
2-(2,2-diphenylbenzo[1,3]dioxol-5-yl)-3,5,7-trihydroxychromen-4-one

: 6743-88-0,22255-13-6,72581-59-0,94131-44-9
guaijaverin

Guidance literature:: Multi-step reaction with 3 steps

1: K₂CO₃ / dimethylformamide

2: H₂ / Pd/C

3: MeONa; MeOH

With methanol; hydrogen; sodium methylate; potassium carbonate; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.05.061

Reference yield:

: 742062-22-2
Acetic acid (2S,3R,4S,5S)-4,5-diacetoxy-2-[2-(2,2-diphenyl-benzo[1,3]dioxol-5-yl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yloxy]-tetrahydro-pyran-3-yl ester

: 6743-88-0,22255-13-6,72581-59-0,94131-44-9
guaijaverin

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd/C

2: MeONa; MeOH

With methanol; hydrogen; sodium methylate; palladium on activated charcoal;
DOI:10.1016/j.bmcl.2004.05.061