Trioxidane

Base Information

• Chemical Name: Trioxidane
• CAS No.: 14699-99-1
• Molecular Formula: H2O3
• Molecular Weight: 50.0141
• DSSTox Substance ID: DTXSID60932994
• Nikkaji Number: J1.680.850D
• Wikipedia: Trioxidane
• Wikidata: Q417642,Q27110056
• RXCUI: 1310514
• Mol file: 14699-99-1.mol

Synonyms:trioxidane;epoxy alcohol;ketoalcohol;oxoalcohol;Lactoperoxidase;Dihydroxy ether;HOOOH;Horseradish peroxidase;Horse radish peroxidase;Myeloperoxidase, human pmn;UNII-JQZ6YM58U5;UNII-2TQ44G23HV;CHEBI:46736;DTXSID60932994;EINECS 232-668-6;14699-99-1;EC 1.11.1.7;E.C. 1.11.1.7;Q417642;Q27110056

Chemical Property of Trioxidane

Chemical Property:

• PSA: 49.69000
• LogP: -0.05100
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 50.000393922
• Heavy Atom Count: 3
• Complexity: 0

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: OOO

Technology Process of Trioxidane

There total 16 articles about Trioxidane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C8H11O3PolSi + water (7732-18-5) → trioxidane (14699-99-1)

Guidance literature:

With methytrioxorhenium(VII); at -30 ℃; for 3h; polystyrene bead

DOI:10.1002/anie.201504084

Reference yield: 45.0%

ozone (10028-15-6) + diphenyl hydrazine (122-66-7) → trioxidane (14699-99-1)

Guidance literature:

In acetic acid methyl ester; ozonation od 1,2-diphenylhydrazine with ozone-nitrogen or ozone-oxygen mixt. in methyl acetate at -78°C;

DOI:10.1021/ja036801u

Reference yield: 45.0%

ozone (10028-15-6) + diphenyl hydrazine (122-66-7) → trioxidane (14699-99-1) + water (7732-18-5) + dihydrogen peroxide (7722-84-1)

Guidance literature:

In [⁽²⁾H₆]acetone; byproducts: PhN(O)NPh; ozonation od 1,2-diphenylhydrazine with ozone-nitrogen or ozone-oxygen mixt. in acetone-d6 at -60°C; monitoring by NMR;

DOI:10.1021/ja036801u

upstream raw materials:

Triethylgerman

ozone

hydroxyl

hydroperoxyl radical

Refernces

Total Synthesis of Prostaglandin F_2α via Nickel-Promoted Stereoselective Cyclization of 1,3-Diene and Aldehyde

10.1055/s-1997-3268

The research aims to achieve the total synthesis of prostaglandin F2a (PGF2a) using a nickel-promoted cyclization method. The study employs key chemicals such as 1,3-cyclohexadiene (1,3-CHD), hydride nickel complex generated from Ni(acac)2 and PPh3, and various reagents like DIBAL-H, PCC, and Wittig reagents. The researchers successfully synthesized PGF2a by first preparing an optically active substrate (16) from chiral epoxy alcohol (10). This substrate underwent nickel-promoted cyclization in the presence of 1,3-CHD to stereoselectively form the key intermediate (18), which contains the a-chain and four contiguous chiral carbon centers of PGF2a. The intermediate was then transformed into PGF2a through a series of reactions. The study concludes that nickel-promoted cyclization is a promising method for constructing cyclopentanoids and provides a new approach for the synthesis of PGF2a, with further studies ongoing to explore its potential.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 14699-99-1 Hydrogen trioxide(6CI,7CI,8CI,9CI)

Send

Send

Metric Ton KG G Pound L ML

Send

Send