6-METHYLAMINO-1,3-DIMETHYLURACIL

Base Information

• Chemical Name: 6-METHYLAMINO-1,3-DIMETHYLURACIL
• CAS No.: 5770-42-3
• Molecular Formula: C7H11 N3 O2
• Molecular Weight: 169.183
• Mol file: 5770-42-3.mol

Synonyms:Uracil,1,3-dimethyl-6-(methylamino)- (6CI,7CI,8CI);1,3-Dimethyl-6-(methylamino)uracil; 6-Methylamino-1,3-dimethyluracil; NSC 70463

Chemical Property of 6-METHYLAMINO-1,3-DIMETHYLURACIL

Chemical Property:

• Vapor Pressure: 0.0127mmHg at 25°C
• Boiling Point: 259.8°Cat760mmHg
• Flash Point: 110.9°C
• PSA: 56.03000
• Density: 1.25g/cm³
• LogP: -0.80130

Purity/Quality:

99% ^*data from raw suppliers

1,3-DIMETHYL-6-(METHYLAMINO)-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-METHYLAMINO-1,3-DIMETHYLURACIL

There total 16 articles about 6-METHYLAMINO-1,3-DIMETHYLURACIL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,3-Dimethyl-6-chlorouracil (6972-27-6) + methylamine (74-89-5) → 1,3-dimethyl-6-methylamino-1H-pyrimidine-2,4-dione (5770-42-3)

Guidance literature:

In methanol; for 16h; Large scale;

Reference yield: 80.0%

1,3-Dimethyl-6-chlorouracil (6972-27-6) + N-methylhydroxyamine hydrochloride (4229-44-1) → 1,3-dimethyl-6-methylamino-1H-pyrimidine-2,4-dione (5770-42-3) + 6-(hydroxy-methyl-amino)-1,3-dimethyl-1H-pyrimidine-2,4-dione (510773-30-5)

Guidance literature:

With sodium hydrogencarbonate; In ethanol; for 3h; Heating;

DOI:10.1002/1099-0690(200301)2003:1<190::AID-EJOC190>3.0.CO;2-W

Reference yield: 55.0%

C14H16N4O4 → 1,3-dimethyl-6-methylamino-1H-pyrimidine-2,4-dione (5770-42-3) + 1,3-dimethyl-6-methylamino-5-phenylamino-1H-pyrimidine-2,4-dione

Guidance literature:

In toluene; for 1h;

DOI:10.1002/1099-0690(200301)2003:1<190::AID-EJOC190>3.0.CO;2-W

upstream raw materials:

1,3-Dimethyl-6-chlorouracil

methylamine

1,3-dimethyl-5-bromo-6-methylaminopyrimidine-2,4-dione

di-(1,3-dimethyl-6-methylaminouracil-5-yl)methane

Downstream raw materials:

NCNMe₂

3,4,6-trimethyl-5,7-dioxo-4,5,6,7-tetrahydro-1,2,3-triazolo<4,5-d>pyrimidine

di-(1,3-dimethyl-6-methylaminouracil-5-yl)methane

4-methyl-N-(2-phenyl-2-(phenylamino)ethyl)benzenesulfonamide