3,12-Dihydroxyspirostan-11-one

Base Information

Chemical Name:3,12-Dihydroxyspirostan-11-one
CAS No.:86023-87-2
Molecular Formula:C₂₇H₄₂O₅
Molecular Weight:446.627
Hs Code.:
NSC Number:96935
DSSTox Substance ID:DTXSID201006594

Synonyms:3,12-dihydroxyspirostan-11-one;86023-87-2;NSC96935;DTXSID201006594;NSC-96935

Suppliers and Price of 3,12-Dihydroxyspirostan-11-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3,12-Dihydroxyspirostan-11-one

Chemical Property:

Vapor Pressure:4.67E-16mmHg at 25°C
Boiling Point:583.7°Cat760mmHg
Flash Point:190.6°C
Density:1.21g/cm³
XLogP3:4.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:446.30322444
Heavy Atom Count:32
Complexity:799

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC2(C(C3C(O2)CC4C3(C(C(=O)C5C4CCC6C5(CCC(C6)O)C)O)C)C)OC1

Technology Process of 3,12-Dihydroxyspirostan-11-one

There total 20 articles about 3,12-Dihydroxyspirostan-11-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 82182-52-3
(3β,5α,12β,25R)-3,12-di(acetoxy)spirostan-11-one

: 4802-74-8
11-ketotigogenin

: 86023-87-2
3β,12β-dihydroxy-11-oxo-(25R)-5α-spirostane

: 4947-79-9
3β-acetoxy-5α,25R-spirostan-11-one

Guidance literature:: With 1-methyl-pyrrolidin-2-one; potassium hydroxide; tetrabutylammonium acetate; acetic acid; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, electrolysis, Pt anode, graphite cathode, constant current 125 mA (25 mA/cm³), 4.1 F/mol, 40 deg C, 2.) MeOH, room temperature, 4 h, 3.) H₂O, overnight;
DOI:10.1021/jo9513469

Reference yield:

: 5130-60-9
3β-acetoxy-11α,23α-dibromo-12-oxo-(25R)-5α-spirostane

: 86023-87-2
3β,12β-dihydroxy-11-oxo-(25R)-5α-spirostane

Guidance literature:: Multi-step reaction with 3 steps

1: aq.-ethanolic KOH-solution

2: ethanolic KOH-solution

3: acetic acid; zinc-powder

With potassium hydroxide; acetic acid; zinc;
DOI:10.1021/ja01116a002

Reference yield:

: 915-35-5
hecogenin acetate

: 86023-87-2
3β,12β-dihydroxy-11-oxo-(25R)-5α-spirostane

Guidance literature:: Multi-step reaction with 2 steps

1: chloroform; bromine / Behandeln des Reaktionsprodukts mit methanol. Kalilauge und anschliessendem Erwaermen mit Kaliumhydroxid

2: acetic acid; zinc-powder

With chloroform; bromine; acetic acid; zinc;
DOI:10.1021/ja01116a002