4802-74-8 Usage
General Description
11-KETOTIGOGENIN is a steroidal sapogenin compound found in various plants, including Yucca gloriosa and Agave americana. It is a precursor to the synthesis of steroid hormones and has been studied for its potential pharmacological properties. Research suggests that 11-KETOTIGOGENIN may have anti-inflammatory, anti-cancer, and anti-viral effects. Additionally, it has been investigated for its cardiovascular and neuroprotective properties. The compound is also used in the production of steroid drugs and may have potential applications in the pharmaceutical industry. Further studies are needed to fully understand the pharmacological effects and potential therapeutic uses of 11-KETOTIGOGENIN.
Check Digit Verification of cas no
The CAS Registry Mumber 4802-74-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,0 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4802-74:
(6*4)+(5*8)+(4*0)+(3*2)+(2*7)+(1*4)=88
88 % 10 = 8
So 4802-74-8 is a valid CAS Registry Number.
InChI:InChI=1/C27H42O4/c1-15-7-10-27(30-14-15)16(2)23-22(31-27)12-20-19-6-5-17-11-18(28)8-9-25(17,3)24(19)21(29)13-26(20,23)4/h15-20,22-24,28H,5-14H2,1-4H3/t15-,16+,17+,18+,19+,20+,22+,23+,24-,25+,26+,27-/m1/s1
4802-74-8Relevant articles and documents
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Djerassi et al.
, p. 5533,5535 (1954)
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Djerassi et al.
, p. 5513 (1951)
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Efficient synthetic approach to potent antiproliferative agent hippuristanol via Hg(II)-catalyzed spiroketalization
Ravindar, Kontham,Reddy, Maddi Sridhar,Lindqvist, Lisa,Pelletier, Jerry,Deslongchamps, Pierre
supporting information; experimental part, p. 4420 - 4423 (2010/12/18)
Figure Presented. The steroidal natural product hippuristanol targets eukaryotic translation initiation factor (eIF)4A which plays a pivotal role in translation in eukaryotic cells. Now an efficient synthesis of hippuristanol from 11-ketotigogenin is reported. The synthesis features a rapid construction of a spiroketal unit via Hg(OTf)2-catalyzed oxidation/ spiroketalization of the 3-alkyn-1,7-diol motif.
11-Ketotigogenin cellobioside (pamaqueside): A potent cholesterol absorption inhibitor in the hamster
McCarthy,DeNinno,Morehouse,Chandler,Bangerter,Wilson,Urban,Walinsky,Cosgrove,Duplantier,Etienne,Fowler,Lambert,O'Donnell,Pezzullo,Watson Jr.,Wilkins,Zaccaro,Zawistoski
, p. 1935 - 1937 (2007/10/03)
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