2-Des(acetylthioMethyl)-2-Methylene Racecadotril

Base Information Edit

Chemical Name:2-Des(acetylthioMethyl)-2-Methylene Racecadotril
CAS No.:87428-99-7
Molecular Formula:C19H19NO3
Molecular Weight:309.365
Hs Code.:
Mol file:87428-99-7.mol

Synonyms:Racecadotril Impurity F;

Suppliers and Price of 2-Des(acetylthioMethyl)-2-Methylene Racecadotril

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Des(acetylthiomethyl)-2-methyleneRacecadotril
250mg
$ 185.00

Total 9 raw suppliers

Chemical Property of 2-Des(acetylthioMethyl)-2-Methylene Racecadotril Edit

Chemical Property:

Melting Point:50-52°C
Boiling Point:524.9±50.0 °C(Predicted)
PKA:13.71±0.46(Predicted)
PSA：58.89000
Density:1.146±0.06 g/cm3(Predicted)
LogP:3.48520
Storage Temp.:Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Purity/Quality:

99.9% ^*data from raw suppliers

2-Des(acetylthiomethyl)-2-methyleneRacecadotril ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An impurity of the antidiarrheal Racecadotril (R070600).

Technology Process of 2-Des(acetylthioMethyl)-2-Methylene Racecadotril

There total 9 articles about 2-Des(acetylthioMethyl)-2-Methylene Racecadotril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.1%

: 2462-31-9
benzyl 2-aminoacetate hydrochloride

: 88320-94-9
2-benzylpropenoyl chloride

: 87428-99-7
2-des(acetylthiomethyl)-2-methylene racecadotril

Guidance literature:: benzyl 2-aminoacetate hydrochloride; With triethylamine; In dichloromethane; at 20 ℃; for 0.5h; Industrial scale;

2-benzylpropenoyl chloride; In dichloromethane; at 5 ℃; for 1h; Industrial scale;

Reference yield: 90.1%

: 1738-76-7
glycine benzyl ester p-toluenesulfonic acid salt

: 88320-94-9
2-benzylpropenoyl chloride

: 87428-99-7
2-des(acetylthiomethyl)-2-methylene racecadotril

Guidance literature:: glycine benzyl ester p-toluenesulfonic acid salt; With triethylamine; In dichloromethane; at 20 ℃; for 0.5h; Industrial scale;

2-benzylpropenoyl chloride; In dichloromethane; at 0 ℃; for 1h; Industrial scale;