Carbamic acid, N-[[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl]-, 1,1-dimethyleth

Base Information

Chemical Name:Carbamic acid, N-[[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl]-, 1,1-dimethyleth
CAS No.:875551-47-6
Molecular Formula:C17H26N2O3
Molecular Weight:306.40000
Hs Code.:

Synonyms:Carbamic acid, N-[[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl]-, 1,1-dimethyleth;

Suppliers and Price of Carbamic acid, N-[[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl]-, 1,1-dimethyleth

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of Carbamic acid, N-[[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl]-, 1,1-dimethyleth

Chemical Property:

PSA：50.80000
LogP:2.74090

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamic acid, N-[[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl]-, 1,1-dimethyleth

There total 1 articles about Carbamic acid, N-[[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl]-, 1,1-dimethyleth which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 146944-34-5
(4-benzylmorpholin-2-ylmethyl)carbamic acid tert-butyl ester

: 875551-47-6
1,1-dimethylethyl {[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl}carbamate

: 186293-56-1
1,1-dimethylethyl {[(2S)-4-(phenylmethyl)-2-morpholinyl]methyl}carbamate

Guidance literature:: With Chiracel OD column; In ethanol; hexane; Resolution of racemate;

Reference yield:

: 875551-47-6
1,1-dimethylethyl {[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl}carbamate

: N-((1S)-1-{[({(2R)-4-[(2-cyanophenyl)sulfonyl]-2-morpholinyl}methyl)amino]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide

Guidance literature:: Multi-step reaction with 6 steps

1: hydrogen / palladium 10% on activated carbon / methanol / 43 h / 760.05 Torr

2: triethylamine / dichloromethane / 16 h / 0 - 20 °C

3: hydrogenchloride / 1,4-dioxane; ethyl acetate / 48 h

4: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine / dichloromethane / 24 h

5: hydrogenchloride / 1,4-dioxane; methanol / 96 h

6: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine / dichloromethane / 24 h

With hydrogenchloride; hydrogen; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; palladium 10% on activated carbon; In 1,4-dioxane; methanol; dichloromethane; ethyl acetate;

Reference yield:

: 875551-47-6
1,1-dimethylethyl {[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl}carbamate

: 911641-00-4
1,1-dimethylethyl ({(2R)-4-[(2-cyanophenyl)sulfonyl]-2-morpholinyl}methyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / palladium 10% on activated carbon / methanol / 43 h / 760.05 Torr

2: triethylamine / dichloromethane / 16 h / 0 - 20 °C

With hydrogen; triethylamine; palladium 10% on activated carbon; In methanol; dichloromethane;