(E)-1-(3-Chlorophenyl)-3-diMethylaMinopropenone

Base Information

• Chemical Name: (E)-1-(3-Chlorophenyl)-3-diMethylaMinopropenone
• CAS No.: 876376-75-9
• Molecular Formula: C11H12ClNO
• Molecular Weight: 209.675
• Hs Code.: 2924299090
• Mol file: 876376-75-9.mol

Synonyms:3'-chloro-3-dimethylaminoacrylophenone;Hg^H`MDHcHhdihTiWPACMPBI`;3-dimethylamino-1-(3-chlorophenyl)propenone;1-(3-chlorophenyl)-3-(dimethylamino)-2-propen-1-one;HMS2423C05;(E)-1-(3-chloro-phenyl)-3-dimethylamino-propenone;

Chemical Property of (E)-1-(3-Chlorophenyl)-3-diMethylaMinopropenone

Chemical Property:

• PSA: 20.31000
• LogP: 2.59800

Purity/Quality:

97% ^*data from raw suppliers

(E)-1-(3-Chlorophenyl)-3-dimethylaminopropenone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-1-(3-Chlorophenyl)-3-diMethylaMinopropenone

There total 2 articles about (E)-1-(3-Chlorophenyl)-3-diMethylaMinopropenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl-formamide dimethyl acetal (4637-24-5) + 3'-Chloroacetophenone (99-02-5) → (E)-1-(3-chlorophenyl)-3-(dimethylamino)prop-2-en-1-one (876376-75-9)

Guidance literature:

In toluene; at 100 ℃;

Reference yield:

para-chloroacetophenone (99-91-2) → (E)-1-(3-chlorophenyl)-3-(dimethylamino)prop-2-en-1-one (876376-75-9)

Guidance literature:

With N,N-dimethyl-formamide dimethyl acetal;

Reference yield: 96.0%

potassium thioacyanate (333-20-0) + (E)-1-(3-chlorophenyl)-3-(dimethylamino)prop-2-en-1-one (876376-75-9) → (Z)-1-(3-chlorophenyl)-3-(dimethylamino)-2-thiocyanatoprop-2-en-1-one

Guidance literature:

With air; In acetonitrile; at 20 ℃; for 2h; Electrochemical reaction;

DOI:10.1055/s-0039-1691486

upstream raw materials:

N,N-dimethyl-formamide dimethyl acetal

3'-Chloroacetophenone

para-chloroacetophenone