CHEMBRDG-BB 4016714

Base Information

• Chemical Name: CHEMBRDG-BB 4016714
• CAS No.: 34171-43-2
• Molecular Formula: C7H10ClN3
• Molecular Weight: 171.63
• Mol file: 34171-43-2.mol

Synonyms:

Chemical Property of CHEMBRDG-BB 4016714

Chemical Property:

• Vapor Pressure: 0.00259mmHg at 25°C
• Boiling Point: 286.8°Cat760mmHg
• Flash Point: 127.2°C
• Density: 1.207g/cm³

Purity/Quality:

(2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CHEMBRDG-BB 4016714

There total 3 articles about CHEMBRDG-BB 4016714 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

2,6-dichloro-5-methylpyrimidine (1780-31-0) + dimethyl amine (124-40-3) → 2-chloro-4-dimethylamino-5-methylpyrimidine (34171-43-2)

Guidance literature:

In tetrahydrofuran; methanol; at 10 ℃; for 1.5h;

Reference yield:

2,6-dichloro-5-methylpyrimidine (1780-31-0) + dimethyl amine (124-40-3) → 4-chloro-2-dimethylamino-5-methylpyrimidine + 2-chloro-4-dimethylamino-5-methylpyrimidine (34171-43-2)

Guidance literature:

2,6-dichloro-5-methylpyrimidine; dimethyl amine; In tetrahydrofuran; water; at 20 ℃; for 120h;

With sodium hydrogencarbonate; In water;

Reference yield:

→ 2-chloro-4-dimethylamino-5-methylpyrimidine (34171-43-2)

Guidance literature:

2,4-Dichlor-5-methylpyrimidin, 25percentaq.Me2NH (1h RT);

upstream raw materials:

2,6-dichloro-5-methylpyrimidine

dimethyl amine

Downstream raw materials:

cis-4-(4-dimethylamino-5-methyl-pyrimidin-2-ylamino)-cyclohexanecarboxylic acid 3-nitro-benzylamide

cis-4-(4-dimethylamino-5-methyl-pyrimidin-2-ylamino)-cyclohexanecarboxylic acid ethyl ester

cis-[4-(4-dimethylamino-5-methyl-pyrimidin-2-ylamino)-cyclohexyl]-carbamic acid tert-butyl ester