2-Phenylnaphtho[2,1-d]thiazole

Base Information

• Chemical Name: 2-Phenylnaphtho[2,1-d]thiazole
• CAS No.: 90016-94-7
• Molecular Formula: C17H11NS
• Molecular Weight: 261.347
• DSSTox Substance ID: DTXSID501306707
• Nikkaji Number: J909.410E
• Mol file: 90016-94-7.mol

Synonyms:2-Phenylnaphtho[2,1-d]thiazole;SCHEMBL24476713;DTXSID501306707;ARL102154;2-phenylnaphtho[2,1-d][1,3]thiazole;90016-94-7

Chemical Property of 2-Phenylnaphtho[2,1-d]thiazole

Chemical Property:

• XLogP3: 5.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 261.06122053
• Heavy Atom Count: 19
• Complexity: 312

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC3=C(S2)C4=CC=CC=C4C=C3

Technology Process of 2-Phenylnaphtho[2,1-d]thiazole

There total 18 articles about 2-Phenylnaphtho[2,1-d]thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

benzaldehyde (100-52-7) + naphthalen-2-ylamine (91-59-8) → 2-phenylnaphtho[2,1-d]thiazole (90016-94-7)

Guidance literature:

With sulfur; acetic acid; dimethyl sulfoxide; In ethanol; 1,2-dichloro-benzene; at 120 ℃; for 72h; Sealed tube;

DOI:10.1021/jacs.0c03418

Reference yield: 97.0%

N-(naphthalen-2-yl)benzothioamide (860723-67-7) → 2-phenylnaphtho[2,1-d]thiazole (90016-94-7)

Guidance literature:

With sodium benzoate; water; In acetonitrile; at 70 ℃; for 4h; Electrochemical reaction; Inert atmosphere; Green chemistry;

DOI:10.1039/c7gc00468k

Reference yield: 97.0%

phenylacetic acid (103-82-2) + naphthalen-2-ylamine (91-59-8) → 2-phenylnaphtho[2,1-d]thiazole (90016-94-7)

Guidance literature:

With sulfur; ammonium iodide; potassium phosphate; dimethyl sulfoxide; In chlorobenzene; at 120 ℃; for 16h; Sealed tube;

DOI:10.1039/d1ob00671a

upstream raw materials:

benzyl-2-naphthylamine

N-(naphthalen-2-yl)benzothioamide

benzylidene(2-naphthyl)amine

2-Amino-1-iodonaphthalene