Oxamide

Base Information

• Chemical Name: Oxamide
• CAS No.: 471-46-5
• Deprecated CAS: 4745-68-0
• Molecular Formula: C2H4N2O2
• Molecular Weight: 88.066
• Hs Code.: 29241900
• European Community (EC) Number: 207-442-5
• NSC Number: 2770
• UNII: SBE4M0223E
• DSSTox Substance ID: DTXSID1060051
• Nikkaji Number: J2.595J
• Wikipedia: Oxamide
• Wikidata: Q423341
• Metabolomics Workbench ID: 56916
• ChEMBL ID: CHEMBL1995464
• Mol file: 471-46-5.mol

Synonyms:oxalic acid diamide;oxamide

Chemical Property of Oxamide

Chemical Property:

• Appearance/Colour: white fine crystalline powder
• Vapor Pressure: 0.0107mmHg at 25°C
• Melting Point: >300 °C(lit.)
• Refractive Index: 1.495
• Boiling Point: 262.699 °C at 760 mmHg
• PKA: 13.28±0.50(Predicted)
• Flash Point: 112.677 °C
• PSA: 86.18000
• Density: 1.395 g/cm³
• LogP: -0.64240
• Storage Temp.: Store below +30°C.
• Solubility.: 0.37g/l
• Water Solubility.: insoluble
• XLogP3: -1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 88.027277375
• Heavy Atom Count: 6
• Complexity: 75.5

Purity/Quality:

99% ^*data from raw suppliers

Oxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 22-36/38-36/37/38
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Compounds
• Canonical SMILES: C(=O)(C(=O)N)N
• Uses: Oxamide is used as a stabilizer for nitrocellulose preparations. It also finds use in APCP rocket motors as a high performance burn rate suppressant.

Technology Process of Oxamide

There total 167 articles about Oxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.9%

1,2-dimorpholinoethane-1,2-dione (6342-79-6) → Oxalamide (471-46-5)

Guidance literature:

With urea; In tetrahydrofuran; at 140 ℃; for 16h; under 7500.75 Torr; Pressure; Temperature; Inert atmosphere;

Reference yield: 95.4%

N,N'-Diphenyloxamid (620-81-5) → Oxalamide (471-46-5)

Guidance literature:

With urea; In tetrahydrofuran; at 70 - 160 ℃; for 16h; under 22502.3 Torr; Inert atmosphere;

Reference yield: 27.0%

L-alanin (56-41-7,25191-17-7,18875-37-1) + formamide (77287-34-4,77287-35-5,60100-09-6) → L-serin (56-45-1,83245-15-2) + L-asparagine (70-47-3,28088-48-4,7006-34-0) + Oxalamide (471-46-5)

Guidance literature:

With sulfuric acid; In water; for 2h; Concentration; Electrolysis; Inert atmosphere;

DOI:10.1246/bcsj.20140164

upstream raw materials:

Glycine anhydride

diketopiperazine

β'-Form des Oximinomalonsaeure-amid-p-toluidids

glycine-glycine-glycine

Downstream raw materials:

triuret

parabanic acid

ethanedinitrile

oxamic acid

Refernces

• 1、 Harada, Kaoru,Ito, Yoshimi,Wada, Toshinori,Munegumi, Toratane. "Efficient dimerization of formic acid in aqueous solution induced by Ar-Arc plasma". . p. 2175 - 2179. Retrieved 2001.
• 2、 Yurtanov, A. I.. "DECOMPOSITION PRODUCTS OF HALONITROACETIC ACID DERIVATIVES". . p. 120 - 122. Retrieved 1992.
• 3、 -. "Preparation method of oxamide". Paragraph 0074; 0075; 0082-0087; 0090. . Retrieved 2019/08/03.
• 4、 Munegumi, Toratane. "Chemical evolution of simple amino acids to asparagine under discharge onto the primitive hydrosphere: Simulation experiments using contact glow discharge". . p. 1208 - 1215. Retrieved 2015/02/19.