Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate

Base Information

Chemical Name:Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate
CAS No.:6947-04-2
Molecular Formula:C₁₀H₁₆O₄
Molecular Weight:200.235
Hs Code.:
NSC Number:57393
DSSTox Substance ID:DTXSID60288721

Synonyms:ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate;6947-04-2;ethyl 1,4-dioxaspiro[4.4]nonane-8-carboxylate;NSC57393;SCHEMBL2680062;DTXSID60288721;PYSBINZYCZKICB-UHFFFAOYSA-N;NSC-57393;AKOS037646133;AS-66774;ethyl 1,4-dioxa-spiro[4.4]nonane-7-carboxylate

Suppliers and Price of Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate

Chemical Property:

Vapor Pressure:0.00551mmHg at 25°C
Boiling Point:274.1°Cat760mmHg
Flash Point:116.6°C
Density:1.15g/cm³
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:200.10485899
Heavy Atom Count:14
Complexity:220

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1CCC2(C1)OCCO2

Technology Process of Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate

There total 6 articles about Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 5400-79-3
ethyl 3-oxocyclopentanecarboxylate

: 107-21-1
ethylene glycol

: 6947-04-2
ethyl 3,3-ethylenedioxycyclopentanecarboxylate

Guidance literature:: With toluene-4-sulfonic acid; In toluene; at 80 ℃; for 3h;

Reference yield:

: 98-78-2
3-Oxo-cyclopentanecarboxylic acid

: 107-21-1
ethylene glycol

: 6947-04-2
ethyl 3,3-ethylenedioxycyclopentanecarboxylate

Guidance literature:: With toluene-4-sulfonic acid; orthoformic acid triethyl ester; In toluene; for 24h; Reflux;

Reference yield:

: 930-30-3
cyclopent-2-enone

: 6947-04-2
ethyl 3,3-ethylenedioxycyclopentanecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / NH₄Cl / acetonitrile; H₂O / 24 h / Ambient temperature

2: 85 percent / p-TsOH / benzene / 2.5 h / Heating

3: 98 percent / 10percent NaOH / 3 h / Heating

4: 1.) 25percent aq. NaOH / 1.) HMPA, 2.) HMPA, 1 h

With sodium hydroxide; ammonium chloride; toluene-4-sulfonic acid; In water; acetonitrile; benzene;
DOI:10.1071/CH9941833