3-Mercapto-1,2-propanediol

Base Information Edit

Chemical Name:3-Mercapto-1,2-propanediol
CAS No.:96-27-5
Deprecated CAS:1320-53-2,53023-42-0
Molecular Formula:C3H8O2S
Molecular Weight:108.161
Hs Code.:29309070
European Community (EC) Number:202-495-0
NSC Number:5370
UNII:AAO1P0WSXJ
DSSTox Substance ID:DTXSID5046512
Nikkaji Number:J3.966G
Wikipedia:3-Mercaptopropane-1,2-diol
Wikidata:Q2745755
NCI Thesaurus Code:C77509
RXCUI:1363062
ChEMBL ID:CHEMBL1398948
Mol file:96-27-5.mol

Synonyms:3-mercapto-1,2-propanediol;alpha-thioglycerol;mercaptoglycerol;monothioglycerol;thioglycerol;thioglycerol sodium salt

Suppliers and Price of 3-Mercapto-1,2-propanediol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Thioglycerol
100g
$ 135.00

TRC
1-Thioglycerol
10g
$ 120.00

TRC
1-Thioglycerol
500g
$ 175.00

TCI Chemical
α-Thioglycerol >95.0%(GC)
500g
$ 175.00

TCI Chemical
alpha-Thioglycerol [Matrix for FABMS and liquid SIMS] >98.0%(GC)(T)
10g
$ 95.00

TCI Chemical
alpha-Thioglycerol [Matrix for FABMS and liquid SIMS] >98.0%(GC)(T)
1g
$ 23.00

TCI Chemical
α-Thioglycerol >95.0%(GC)
25g
$ 28.00

TCI Chemical
α-Thioglycerol >95.0%(GC)
100g
$ 71.00

SynQuest Laboratories
3-Thiopropane-1,2-diol 97%
25 mL
$ 56.00

SynQuest Laboratories
3-Thiopropane-1,2-diol 97%
10 mL
$ 24.00

Total 123 raw suppliers

Chemical Property of 3-Mercapto-1,2-propanediol Edit

Chemical Property:

Appearance/Colour:clear colorless to yellowish viscous solution
Vapor Pressure:0.00431mmHg at 25°C
Melting Point:<25 °C
Refractive Index:n20/D 1.527(lit.)
Boiling Point:247 °C at 760 mmHg
PKA:pK1:9.43 (25°C,μ=0.5)
Flash Point:126.3 °C
PSA：79.26000
Density:1.236 g/cm³
LogP:-0.73060
Storage Temp.:2-8°C
Sensitive.:Air Sensitive & Hygroscopic
Solubility.:absolute ethanol: 1 mL/mL
Water Solubility.:slightly soluble
XLogP3:-0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:108.02450067
Heavy Atom Count:6
Complexity:32

Purity/Quality:

99.9% ^*data from raw suppliers

1-Thioglycerol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi
Statements: 21/22-36/37/38
Safety Statements: 26-36-23

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Other Classes -> Sulfur Compounds (Alcohols)
Canonical SMILES:C(C(CS)O)O
Description 1-Thioglycerol is a reagent used in fluorescence, spectroscopy, and microbiology techniques. Varying the concentration of 1-thioglycerol in the preparation of CdSe/CdS core-shell ultrasmall quantum dots (CS-USQDs) allows a precise way to control the size of the shell, with shell size increasing with increased concentration. It is used as a capping agent in the synthesis of nanocrystals analyzed via Raman and UV/Vis spectroscopy. Biologically, 1-thioglycerol stimulates porphyrin synthesis and increases glutamyl-tRNA reductase activity in E. coli grown in an aerobic environment. It was previously a component in hair permanents used to produce waves or curls.
Uses 3-Mercapto-1,2-propanediol has been used in a study to assess the manipulation of aqueous growth of CdTe nanocrystals. It has also been used in a study that investigated the effect of surface attachment on ligand binding 3-Mercapto-1,2-propanediol can be used as antioxidant preservative; reagent in analytical chemistry, cell culture research. Matrix substrate in fast atom bombardment mass spectrometry. It generally used as a size-regulating capping agent for nanocrystals. 1-Thioglycerol is also used in bacteriology experiments to induce the synthesis of porphyrin compounds in aerobically growing Escherichia coli. Also used to study the pH-sensitive photoluminescence of aqueous thiol-capped CdTe nanocrystals. 1-Thioglycerol is used to develop and test thiol functionalized copolymers. 1-Thioglycerol is used as a post-modification agent in the generation of non-standard peptide foldamers.Potential substitute for 2-mercaptoethanol, probe for the study of lymphocyte activation.

Technology Process of 3-Mercapto-1,2-propanediol

There total 10 articles about 3-Mercapto-1,2-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.4%