n'-Benzoylpyridine-2-carbohydrazide

Base Information

• Chemical Name: n'-Benzoylpyridine-2-carbohydrazide
• CAS No.: 54571-23-2
• Molecular Formula: C13H11N3O2
• Molecular Weight: 241.2453
• NSC Number: 90913
• DSSTox Substance ID: DTXSID20293598
• Wikidata: Q82032445
• Mol file: 54571-23-2.mol

Synonyms:N'-(phenylcarbonyl)pyridine-2-carbohydrazide;54571-23-2;n'-benzoylpyridine-2-carbohydrazide;NSC90913;2-Pyridinecarboxylic acid, 2-benzoylhydrazide;NCIOpen2_005677;DTXSID20293598;N-benzoyl-N'-picolinoyl hydrazine;NSC-90913;STK088444;AKOS005393658

Chemical Property of n'-Benzoylpyridine-2-carbohydrazide

Chemical Property:

• Boiling Point: 517.1°Cat760mmHg
• Flash Point: 266.6°C
• Density: 1.261g/cm³
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 241.085126602
• Heavy Atom Count: 18
• Complexity: 301

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NNC(=O)C2=CC=CC=N2

Technology Process of n'-Benzoylpyridine-2-carbohydrazide

There total 2 articles about n'-Benzoylpyridine-2-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Picolinic acid (98-98-6) + benzoic acid hydrazide (613-94-5) → pyridine-2-carboxylic acid N'-benzoyl-hydrazide (54571-23-2)

Guidance literature:

With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃;

DOI:10.1016/j.tetlet.2010.06.139

Reference yield:

→ pyridine-2-carboxylic acid N'-benzoyl-hydrazide (54571-23-2)

Guidance literature:

Pyridincarbonsaeure-2-hydrazid, Py., Benzoylchlorid;

Reference yield:

pyridine-2-carboxylic acid N'-benzoyl-hydrazide (54571-23-2) → 2-(4-dimethylamino-penyl)-5-(2-pyridinyl)-1,3,4-oxadiazole (25433-30-1)

Guidance literature:

With PPA;

DOI:10.1246/bcsj.47.2724

upstream raw materials:

2-Picolinic acid

benzoic acid hydrazide

Downstream raw materials:

2-(4-dimethylamino-penyl)-5-(2-pyridinyl)-1,3,4-oxadiazole