N-[2-oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide

Base Information

Chemical Name:N-[2-oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide
CAS No.:913092-75-8
Molecular Formula:C15H18N2O3
Molecular Weight:274.32
Hs Code.:
DSSTox Substance ID:DTXSID40475536

Synonyms:N-[2-oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide;913092-75-8;SCHEMBL4599928;DTXSID40475536;ZSENKHNQBGKMRD-UHFFFAOYSA-N

Suppliers and Price of N-[2-oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[2-oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide

Chemical Property:

XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:274.13174244
Heavy Atom Count:20
Complexity:389

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)NCC(=O)N1CCC(=O)C(C1)C2=CC=CC=C2

Technology Process of N-[2-oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide

There total 1 articles about N-[2-oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 910875-39-7
4-oxo-3-phenylpiperidine hydrochloride

: 543-24-8
N-acetylglycine

: 913092-75-8
N-[2-oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In acetonitrile; at 50 ℃; for 2h;

Reference yield:

: 913092-75-8
N-[2-oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide

: 2627-86-3
(S)-1-phenyl-ethylamine

: 913092-76-9
N-[2-oxo-2-((3R,4S)-3-phenyl-4-{[(1S)-1-phenylethyl]amino}piperidin-1-yl)ethyl]acetamide

Guidance literature:: N-[2-oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide; (S)-1-phenyl-ethylamine; With toluene-4-sulfonic acid; In toluene; for 3h; Heating / reflux; Dean-Stark trap;

With hydrogen; triethylamine; Raney nickel; In ethanol; toluene; at 25 - 50 ℃; under 3750.38 - 7500.75 Torr;

In water; at 10 - 35 ℃; for 2.5h; Heating / reflux;