N-Acetyl-N-ethylacetamide

Base Information

• Chemical Name: N-Acetyl-N-ethylacetamide
• CAS No.: 1563-83-3
• Molecular Formula: C6H11 N O2
• Molecular Weight: 129.159
• Hs Code.: 2925190090
• European Community (EC) Number: 216-354-6
• DSSTox Substance ID: DTXSID20166071
• Nikkaji Number: J206.799D
• Wikidata: Q83035310
• Mol file: 1563-83-3.mol

Synonyms:N-Acetyl-N-ethylacetamide;1563-83-3;N-acetyl-N-ethyl-acetamide;Acetamide, N-acetyl-N-ethyl-;EINECS 216-354-6;AI3-28891;N-Ethyldiacetamide;SCHEMBL1866878;DTXSID20166071;ADAL1185313

Chemical Property of N-Acetyl-N-ethylacetamide

Chemical Property:

• Vapor Pressure: 0.387mmHg at 25°C
• Refractive Index: 1.4513
• Boiling Point: 197°Cat760mmHg
• Flash Point: 74.4°C
• PSA: 37.38000
• Density: 1g/cm³
• LogP: 0.40130
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 129.078978594
• Heavy Atom Count: 9
• Complexity: 117

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(C(=O)C)C(=O)C

Technology Process of N-Acetyl-N-ethylacetamide

There total 7 articles about N-Acetyl-N-ethylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

diethylacetamide (685-91-6) → N-ethyl-diacetamide (1563-83-3)

Guidance literature:

With pyridine; N-hydroxyphthalimide; sodium perchlorate; In acetonitrile; controlled potential electrolysis, electrodes: glassy-carbon vs. SCE;

Reference yield:

diethyl ether (60-29-7,927820-24-4) + ethylamine (75-04-7,85404-22-4) + acetyl chloride (75-36-5) → N-ethyl-diacetamide (1563-83-3) + ethanamine hydrochloride (557-66-4)

Guidance literature:

DOI:10.1021/ja02211a014

Reference yield:

acetyl chloride (75-36-5) + N-ethylacetamide (625-50-3) → N-ethyl-diacetamide (1563-83-3)

Guidance literature:

With pyridine; toluene; at 60 ℃;

DOI:10.1021/ja01289a062

upstream raw materials:

acetic anhydride

ethyl isocyanate

N-ethylacetamide

diethyl ether