Piperidine, 1-(beta-ethoxyphenethyl)-

Base Information

• Chemical Name: Piperidine, 1-(beta-ethoxyphenethyl)-
• CAS No.: 6722-47-0
• Molecular Formula: C₁₅H₂₃NO
• Molecular Weight: 233.354
• Hs Code.: 2933399090
• NSC Number: 220266
• Nikkaji Number: J50.663J
• Mol file: 6722-47-0.mol

Synonyms:6722-47-0;Piperidine, 1-(2-ethoxy-2-phenylethyl)-;Piperidine, 1-(beta-ethoxyphenethyl)-;1-(beta-Ethoxyphenethyl)piperidine;1-(beta-Ethoxyphenylethyl)piperidine;1-(2-ethoxy-2-phenylethyl)piperidine;NSC 220266;BRN 0176227;NSC220266;5-20-02-00204 (Beilstein Handbook Reference);WLN: T6NTJ A1YR&O2;SCHEMBL12847339;1-(.beta.-Ethoxyphenethyl)piperidine;NSC-220266;Piperidine, 1-(.beta.-ethoxyphenethyl)-

Chemical Property of Piperidine, 1-(beta-ethoxyphenethyl)-

Chemical Property:

• Vapor Pressure: 0.00072mmHg at 25°C
• Boiling Point: 307.5°Cat760mmHg
• Flash Point: 90.8°C
• PSA: 12.47000
• Density: 0.989g/cm³
• LogP: 3.18800
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 233.177964357
• Heavy Atom Count: 17
• Complexity: 195

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(CN1CCCCC1)C2=CC=CC=C2

Technology Process of Piperidine, 1-(beta-ethoxyphenethyl)-

There total 3 articles about Piperidine, 1-(beta-ethoxyphenethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

piperidine (110-89-4) + 2-ethoxy-2-phenylethyl bromide (6589-30-6) → 1-(2-ethoxy-2-phenyl-ethyl)-piperidine (6722-47-0)

Guidance literature:

With toluene;

DOI:10.1021/ja01154a125

Reference yield:

1-piperidinyl-acetaldehyde diethyl acetal (3616-58-8) + phenylmagnesium bromide → 1-(2-ethoxy-2-phenyl-ethyl)-piperidine (6722-47-0)

Guidance literature:

With diethyl ether; Erhitzen des vom Aether befreiten Reaktionsgemisches mit Xylol auf 140grad.;

DOI:10.1021/ja01154a125

Reference yield:

→ 1-(2-ethoxy-2-phenyl-ethyl)-piperidine (6722-47-0)

Guidance literature:

aus /BRN= 637222/, Piperidin;

upstream raw materials:

piperidine

2-ethoxy-2-phenylethyl bromide

1-piperidinyl-acetaldehyde diethyl acetal

Downstream raw materials:

1-(β-ethoxy-phenethyl)-1-methyl-piperidinium; iodide