2-Bromo-6-methoxypyrazine

Base Information

Chemical Name:2-Bromo-6-methoxypyrazine
CAS No.:91678-76-1
Molecular Formula:C₅H₅BrN₂O
Molecular Weight:189.011
Hs Code.:2933990090
European Community (EC) Number:811-378-9
DSSTox Substance ID:DTXSID70536705
Wikidata:Q82411447
Mol file:91678-76-1.mol

Synonyms:2-Bromo-6-methoxypyrazine;91678-76-1;Pyrazine, 2-bromo-6-methoxy-;SCHEMBL421693;DTXSID70536705;MFCD10688549;AKOS006305753;PS-4983;CS-0150245;O10694;A934265

Suppliers and Price of 2-Bromo-6-methoxypyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-bromo-6-methoxypyrazine
500mg
$ 330.00

TRC
2-bromo-6-methoxypyrazine
100mg
$ 90.00

TRC
2-bromo-6-methoxypyrazine
50mg
$ 65.00

SynQuest Laboratories
2-Bromo-6-methoxypyrazine 97%
250 mg
$ 104.00

Matrix Scientific
2-Bromo-6-methoxypyrazine
1g
$ 323.00

Matrix Scientific
2-Bromo-6-methoxypyrazine
10g
$ 1722.00

Matrix Scientific
2-Bromo-6-methoxypyrazine
5g
$ 1078.00

Crysdot
2-Bromo-6-methoxypyrazine 95+%
25g
$ 1126.00

Crysdot
2-Bromo-6-methoxypyrazine 95+%
10g
$ 700.00

Crysdot
2-Bromo-6-methoxypyrazine 95+%
5g
$ 465.00

Total 12 raw suppliers

Chemical Property of 2-Bromo-6-methoxypyrazine

Chemical Property:

Boiling Point:199.1±35.0 °C(Predicted)
PKA:-1.84±0.10(Predicted)
PSA：35.01000
Density:1.628±0.06 g/cm3(Predicted)
LogP:1.24770
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:187.95853
Heavy Atom Count:9
Complexity:91

Purity/Quality:

98% ^*data from raw suppliers

2-bromo-6-methoxypyrazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CN=CC(=N1)Br

Technology Process of 2-Bromo-6-methoxypyrazine

There total 1 articles about 2-Bromo-6-methoxypyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 23229-25-6
2,6-dibromopyrazine

: 124-41-4
sodium methylate

: 91678-76-1
2-bromo-6-methoxypyrazine

Guidance literature:: With methanol; at 40 ℃; for 1h;

Reference yield: 32.0%

: 91678-76-1
2-bromo-6-methoxypyrazine

: 73183-34-3
bis(pinacol)diborane

: 960503-91-7
2-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; at 110 ℃; for 2.5h; Inert atmosphere;

Reference yield:

: 91678-76-1
2-bromo-6-methoxypyrazine

: potassium (6-methoxypyrazin-2-yl)trifluoroborate

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran; hexane / 1 h / -100 °C / Inert atmosphere

2: tetrahydrofuran; dimethyl sulfoxide / 1 h / 120 °C

3: L-Tartaric acid / tetrahydrofuran; acetonitrile; water / 24 h / 35 °C

With L-Tartaric acid; In tetrahydrofuran; hexane; water; dimethyl sulfoxide; acetonitrile;