2,4,6-Trichloropyridin-3-amine

Base Information

• Chemical Name: 2,4,6-Trichloropyridin-3-amine
• CAS No.: 91872-08-1
• Molecular Formula: C5H3Cl3N2
• Molecular Weight: 197.451
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID00527641
• Wikidata: Q82396859
• Mol file: 91872-08-1.mol

Synonyms:2,4,6-Trichloropyridin-3-amine;91872-08-1;MFCD20703662;3-Pyridinamine, 2,4,6-trichloro-;SCHEMBL9476338;DTXSID00527641;ZB1341;AKOS016007948;SB52375;DS-16776;SY118856;CS-0045862;W18044;A860207

Chemical Property of 2,4,6-Trichloropyridin-3-amine

Chemical Property:

• Melting Point: 77.5-78 °C
• Boiling Point: 304.7±37.0 °C(Predicted)
• PKA: -1.95±0.10(Predicted)
• PSA: 38.91000
• Density: 1.634±0.06 g/cm3(Predicted)
• LogP: 3.20520
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 195.936181
• Heavy Atom Count: 10
• Complexity: 122

Purity/Quality:

97% ^*data from raw suppliers

2,4,6-Trichloropyridin-3-amine 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=C(C(=C(N=C1Cl)Cl)N)Cl

Technology Process of 2,4,6-Trichloropyridin-3-amine

There total 4 articles about 2,4,6-Trichloropyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-dichloropyridin-3-ylamine (173772-63-9) → 2,4,6-trichloro-[3]pyridylamine (91872-08-1)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide; acetic acid;

Reference yield:

2,4-dihydroxy-3-nitropyridine (89282-12-2) → 2,4,6-trichloro-[3]pyridylamine (91872-08-1)

Guidance literature:

Multi-step reaction with 3 steps

1: phosphoryl chloride

2: iron-powder; acetic acid

3: HCl; acetic acid; aqueous H₂O₂

With hydrogenchloride; dihydrogen peroxide; iron; acetic acid; trichlorophosphate;

Reference yield:

2,4-dichloro-3-nitro-pyridine (5975-12-2) → 2,4,6-trichloro-[3]pyridylamine (91872-08-1)

Guidance literature:

Multi-step reaction with 2 steps

1: iron-powder; acetic acid

2: HCl; acetic acid; aqueous H₂O₂

With hydrogenchloride; dihydrogen peroxide; iron; acetic acid;

upstream raw materials:

2,4-dichloropyridin-3-ylamine

hydrogenchloride

dihydrogen peroxide

acetic acid

Downstream raw materials:

2,3,4,6-Tetrachloropyridine