6-[2-Acetyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-5-yl]-2-(4-methoxyphenyl)chromen-4-one

Base Information

Chemical Name:6-[2-Acetyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-5-yl]-2-(4-methoxyphenyl)chromen-4-one
CAS No.:154185-85-0
Molecular Formula:C₂₈H₂₄N₂O₅
Molecular Weight:468.509
Hs Code.:
DSSTox Substance ID:DTXSID30934945
Mol file:154185-85-0.mol

Synonyms:154185-85-0;6-[2-acetyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-5-yl]-2-(4-methoxyphenyl)chromen-4-one;1H-Pyrazole, 4,5-dihydro-1-acetyl-5-(4-methoxyphenyl)-3-(2-(4-methoxyphenyl)-4-oxo-4H-1-benzopyran-6-yl)-;1H-Pyrazole, 4,5-dihydro-1-acetyl-5-(4-methoxyphenyl)-3-(2-(4-methoxyp henyl)-4-oxo-4H-1-benzopyran-;DTXSID30934945;VWDVTDKMXARLMB-UHFFFAOYSA-N;C28H24N2O5;C28-H24-N2-O5;LS-128433;6-[1-Acetyl-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl]-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one

Suppliers and Price of 6-[2-Acetyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-5-yl]-2-(4-methoxyphenyl)chromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1H-PYRAZOLE, 4,5-DIHYDRO-1-ACETYL-5-(4-METHOXYPHENYL)-3-(2-(4-METHOXYP HENYL)-4-OXO-4H-1-BENZOPYRAN-6-YL)- 95.00%
5MG
$ 505.09

Total 2 raw suppliers

Chemical Property of 6-[2-Acetyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-5-yl]-2-(4-methoxyphenyl)chromen-4-one

Chemical Property:

Vapor Pressure:7.14E-17mmHg at 25°C
Boiling Point:651.8°Cat760mmHg
Flash Point:348°C
PSA：81.34000
Density:1.27g/cm³
LogP:4.54830
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:468.16852187
Heavy Atom Count:35
Complexity:853

Purity/Quality:

99% ^*data from raw suppliers

1H-PYRAZOLE, 4,5-DIHYDRO-1-ACETYL-5-(4-METHOXYPHENYL)-3-(2-(4-METHOXYP HENYL)-4-OXO-4H-1-BENZOPYRAN-6-YL)- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N1C(CC(=N1)C2=CC3=C(C=C2)OC(=CC3=O)C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

Technology Process of 6-[2-Acetyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-5-yl]-2-(4-methoxyphenyl)chromen-4-one

There total 4 articles about 6-[2-Acetyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-5-yl]-2-(4-methoxyphenyl)chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 64-19-7,77671-22-8
acetic acid

: 154185-52-1
2-(4-Methoxy-phenyl)-6-[(E)-3-(4-methoxy-phenyl)-acryloyl]-chromen-4-one

: 154185-85-0
6-[1-Acetyl-5-(4-methoxy-phenyl)-4,5-dihydro-1H-pyrazol-3-yl]-2-(4-methoxy-phenyl)-chromen-4-one

Guidance literature:: With hydrazine hydrate; for 7h; Heating;

Reference yield:

: 30186-16-4
2,4-diacetylphenol

: 154185-85-0
6-[1-Acetyl-5-(4-methoxy-phenyl)-4,5-dihydro-1H-pyrazol-3-yl]-2-(4-methoxy-phenyl)-chromen-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / KOH / methanol

2: 88 percent / iodine / dimethylsulfoxide / 0.25 h

3: 82 percent / 99percent hydrazine hydrate / 7 h / Heating

With potassium hydroxide; iodine; hydrazine hydrate; In methanol; dimethyl sulfoxide;

Reference yield:

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 154185-85-0
6-[1-Acetyl-5-(4-methoxy-phenyl)-4,5-dihydro-1H-pyrazol-3-yl]-2-(4-methoxy-phenyl)-chromen-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / AlCl₃ / CS₂ / 1 h / Heating

2: 89 percent / KOH / methanol

3: 88 percent / iodine / dimethylsulfoxide / 0.25 h

4: 82 percent / 99percent hydrazine hydrate / 7 h / Heating

With potassium hydroxide; aluminium trichloride; iodine; hydrazine hydrate; In methanol; carbon disulfide; dimethyl sulfoxide;