1-Hydroxyfluromidine

Base Information

Chemical Name:1-Hydroxyfluromidine
CAS No.:35195-95-0
Molecular Formula:C7H3 Cl F3 N3 O
Molecular Weight:0
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80188698
Wikidata:Q83060532
Mol file:35195-95-0.mol

Synonyms:1-hydroxy-2-trifluoromethylimidazo(4,5-b)-6-chloropyridine;1-hydroxyfluromidine

Suppliers and Price of 1-Hydroxyfluromidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Hydroxyfluromidine

Chemical Property:

Vapor Pressure:0.000265mmHg at 25°C
Boiling Point:313.7°Cat760mmHg
Flash Point:143.5°C
PSA：50.94000
Density:1.83g/cm³
LogP:2.34080
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:0
Exact Mass:236.9916739
Heavy Atom Count:15
Complexity:252

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=NC2=C1N(C(=N2)C(F)(F)F)O)Cl

Technology Process of 1-Hydroxyfluromidine

There total 4 articles about 1-Hydroxyfluromidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 35195-91-6
5-chloro-3-nitro-2-(trifluoroacetamido)pyridine

: 35195-95-0
6-CHLORO-1-HYDROXY-2-(TRIFLUOROMETHYL)-1H-IMIDAZO(4,5-b)-PYRIDINE

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1016/S0960-894X(97)00082-6

Reference yield:

: 1072-98-6
5-chloro-2-pyridylamine

: 35195-95-0
6-CHLORO-1-HYDROXY-2-(TRIFLUOROMETHYL)-1H-IMIDAZO(4,5-b)-PYRIDINE

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / HNO₃, H₂SO₄

2: 83 percent / pyridine

3: 67 percent / H₂ / Pd/C / ethanol

With sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In pyridine; ethanol;
DOI:10.1016/S0960-894X(97)00082-6

Reference yield:

: 5409-39-2
2-amino-5-chloro-3-nitropyridine

: 35195-95-0
6-CHLORO-1-HYDROXY-2-(TRIFLUOROMETHYL)-1H-IMIDAZO(4,5-b)-PYRIDINE

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / pyridine

2: 67 percent / H₂ / Pd/C / ethanol

With hydrogen; palladium on activated charcoal; In pyridine; ethanol;
DOI:10.1016/S0960-894X(97)00082-6