2-{2-[Diphenyl(pyridin-4-yl)methoxy]ethoxy}ethan-1-ol

Base Information

Chemical Name:2-{2-[Diphenyl(pyridin-4-yl)methoxy]ethoxy}ethan-1-ol
CAS No.:921588-04-7
Molecular Formula:C22H23NO3
Molecular Weight:349.43
Hs Code.:
DSSTox Substance ID:DTXSID50582669
Wikidata:Q82474166

Synonyms:921588-04-7;2-{2-[Diphenyl(pyridin-4-yl)methoxy]ethoxy}ethan-1-ol;DTXSID50582669

Suppliers and Price of 2-{2-[Diphenyl(pyridin-4-yl)methoxy]ethoxy}ethan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-{2-[Diphenyl(pyridin-4-yl)methoxy]ethoxy}ethan-1-ol

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:349.16779360
Heavy Atom Count:26
Complexity:354

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=NC=C3)OCCOCCO

Technology Process of 2-{2-[Diphenyl(pyridin-4-yl)methoxy]ethoxy}ethan-1-ol

There total 1 articles about 2-{2-[Diphenyl(pyridin-4-yl)methoxy]ethoxy}ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 64991-61-3
diphenyl(4-pyridyl)methyl chloride hydrochloride

: 111-46-6
diethylene glycol

: 921588-04-7
2-[2-[1,1-(diphenyl)-1-(4-pyridyl)methoxy]ethoxy]ethanol

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1021/jm0610550

Reference yield:

: 921588-04-7
2-[2-[1,1-(diphenyl)-1-(4-pyridyl)methoxy]ethoxy]ethanol

: 4330-20-5
N-3-benzoylthymine

: 3-benzoyl-1-{2-[2-(diphenyl-pyridin-4-yl-methoxy)-ethoxy]-ethyl}-5-methyl-1H-pyrimidine-2,4-dione

Guidance literature:: With PS-Ph₃P; di-isopropyl azodicarboxylate; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jm0610550

Reference yield:

: 921588-04-7
2-[2-[1,1-(diphenyl)-1-(4-pyridyl)methoxy]ethoxy]ethanol

: 1-[2-[2-[1,1-(diphenyl)-1-(4-pyridyl)methoxy]ethoxy]ethyl]thymine

Guidance literature:: Multi-step reaction with 2 steps

1: PS-Ph₃P; diisopropyl azodicarboxylate / tetrahydrofuran / 20 °C

2: aq. NaOH / dioxane

With sodium hydroxide; PS-Ph₃P; di-isopropyl azodicarboxylate; In tetrahydrofuran; 1,4-dioxane; 1: Mitsunobu reaction;
DOI:10.1021/jm0610550