Benzyl 2-methyl-2-[(pyridin-3-yl)oxy]propanoate

Base Information

Chemical Name:Benzyl 2-methyl-2-[(pyridin-3-yl)oxy]propanoate
CAS No.:922502-05-4
Molecular Formula:C16H17NO3
Molecular Weight:271.316
Hs Code.:
DSSTox Substance ID:DTXSID40582638
Wikidata:Q82474121

Synonyms:922502-05-4;Benzyl 2-methyl-2-[(pyridin-3-yl)oxy]propanoate;DTXSID40582638

Suppliers and Price of Benzyl 2-methyl-2-[(pyridin-3-yl)oxy]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzyl 2-methyl-2-[(pyridin-3-yl)oxy]propanoate

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:271.12084340
Heavy Atom Count:20
Complexity:311

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C(=O)OCC1=CC=CC=C1)OC2=CN=CC=C2

Technology Process of Benzyl 2-methyl-2-[(pyridin-3-yl)oxy]propanoate

There total 3 articles about Benzyl 2-methyl-2-[(pyridin-3-yl)oxy]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 922502-03-2
2-(pyridin-3-yloxy)-propionic acid benzyl ester

: 74-88-4
methyl iodide

: 922502-05-4
2-methyl-2-(pyridin-3-yloxy)-propionic acid benzyl ester

Guidance literature:: With potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -78 - 20 ℃; for 2h;
DOI:10.1021/jm060996+

Reference yield:

: 109-00-2
3-HYDROXYPYRIDINE

: 922502-05-4
2-methyl-2-(pyridin-3-yloxy)-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: PPh₃; diethyl azodicarboxylate / CH₂Cl₂ / 4 h / 0 - 20 °C

2: potassium hexamethyldisilazide / tetrahydrofuran; toluene / 2 h / -78 - 20 °C

With potassium hexamethylsilazane; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/jm060996+

Reference yield:

: 2051-96-9
benzyl lactate

: 922502-05-4
2-methyl-2-(pyridin-3-yloxy)-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: PPh₃; diethyl azodicarboxylate / CH₂Cl₂ / 4 h / 0 - 20 °C

2: potassium hexamethyldisilazide / tetrahydrofuran; toluene / 2 h / -78 - 20 °C

With potassium hexamethylsilazane; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/jm060996+