2-(4-Methylphenoxy)ethanol

Base Information

• Chemical Name: 2-(4-Methylphenoxy)ethanol
• CAS No.: 15149-10-7
• Molecular Formula: C9H12O2
• Molecular Weight: 152.193
• Hs Code.: 2909498090
• European Community (EC) Number: 239-209-9
• NSC Number: 68802
• DSSTox Substance ID: DTXSID9065861
• Nikkaji Number: J100.040C
• Wikidata: Q63392788
• Mol file: 15149-10-7.mol

Synonyms:2-(4-methylphenoxy)ethanol

Chemical Property of 2-(4-Methylphenoxy)ethanol

Chemical Property:

• Vapor Pressure: 0.00522mmHg at 25°C
• Melting Point: 45 °C
• Refractive Index: 1.523
• Boiling Point: 263.3 °C at 760 mmHg
• PKA: 14.30±0.10(Predicted)
• Flash Point: 114.3 °C
• PSA: 29.46000
• Density: 1.058 g/cm³
• LogP: 1.36610
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 152.083729621
• Heavy Atom Count: 11
• Complexity: 95.7

Purity/Quality:

97% ^*data from raw suppliers

Ethylene Glycol Mono-p-tolyl Ether ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38-41
• Safety Statements: 26-36-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)OCCO

Technology Process of 2-(4-Methylphenoxy)ethanol

There total 14 articles about 2-(4-Methylphenoxy)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

p-Methylphenoxyessigsaeureethylester → 2-(4-methylphenoxy)ethanol (15149-10-7)

Guidance literature:

With lithium aluminium tetrahydride;

Reference yield: 96.0%

para-bromotoluene (106-38-7) + ethylene glycol (107-21-1) → 2-(4-methylphenoxy)ethanol (15149-10-7)

Guidance literature:

With potassium carbonate; copper dichloride; at 130 ℃; for 20h; Reagent/catalyst; Temperature; Inert atmosphere; Schlenk technique;

DOI:10.1039/c4ob00649f

Reference yield: 88.0%

p-cresol (106-44-5) + 2-chloro-ethanol (107-07-3) → 2-(4-methylphenoxy)ethanol (15149-10-7)

Guidance literature:

With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; In N,N-dimethyl-formamide; for 4 - 7h; Heating / reflux;

upstream raw materials:

oxirane

p-cresol

sodium 4-methylphenoxide

2-(4-methylphenoxy)acetic acid

Downstream raw materials:

carbamic acid-(2-p-tolyloxy-ethyl ester)

1-chloro-2-(p-methyl)phenoxyethan

1-p-tolyloxy-2-vinyloxy-ethane

Sodium; p-tolyloxy-acetate