N-Methyl-9-phenyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine hydrochloride

Base Information

Chemical Name:N-Methyl-9-phenyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine hydrochloride
CAS No.:73426-02-5
Molecular Formula:C₁₉H₂₀N₂S*ClH
Molecular Weight:344.908
Hs Code.:
DSSTox Substance ID:DTXSID40994176
Mol file:73426-02-5.mol

Synonyms:73426-02-5;N-Methyl-9-phenyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine hydrochloride;Thiopyrano(2,3-b)indole-4-methylamine, 2,3,4,9-tetrahydro-N-methyl-9-phenyl-, hydrochloride;Thiopyrano(2,3-b)indole, 2,3,4,9-tetrahydro-4-((methylamino)methyl)-9-phenyl-, monohydrochloride;DTXSID40994176;LS-153301;N-Methyl-1-(9-phenyl-2,3,4,9-tetrahydrothiopyrano[2,3-b]indol-4-yl)methanamine--hydrogen chloride (1/1)

Suppliers and Price of N-Methyl-9-phenyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,3,4,9-TETRAHYDRO-N-METHYL-9-PHENYL-THIOPYRANO(2,3-B)INDOLE-4-METHYLAMINE HYDROCHLORIDE 95.00%
5MG
$ 503.94

Total 1 raw suppliers

Chemical Property of N-Methyl-9-phenyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine hydrochloride

Chemical Property:

Vapor Pressure:8.79E-09mmHg at 25°C
Boiling Point:463.8°C at 760 mmHg
Flash Point:234.3°C
PSA：42.26000
LogP:5.62220
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:344.1113975
Heavy Atom Count:23
Complexity:368

Purity/Quality:: 2,3,4,9-TETRAHYDRO-N-METHYL-9-PHENYL-THIOPYRANO(2,3-B)INDOLE-4-METHYLAMINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNCC1CCSC2=C1C3=CC=CC=C3N2C4=CC=CC=C4.Cl

Technology Process of N-Methyl-9-phenyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine hydrochloride

There total 4 articles about N-Methyl-9-phenyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 4-formyl-9-phenyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

: 74-89-5
methylamine

: 73426-02-5
4-(N-methylaminomethyl)-9-phenyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole hydrochloride

Guidance literature:: With hydrogenchloride; sodium tetrahydroborate;
DOI:10.1248/cpb.32.877

Reference yield:

: 73425-20-4
1-phenylindoline-2-thione

: 73426-02-5
4-(N-methylaminomethyl)-9-phenyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / K₂CO₃

2: toluene; pyridine / 0.5 h / Heating

3: 76 percent / 1) NaBH₄; 2) HCl

With hydrogenchloride; sodium tetrahydroborate; potassium carbonate; In pyridine; toluene;
DOI:10.1248/cpb.32.877

Reference yield:

: 3335-98-6
1-phenyl-1,3-dihydro-indol-2-one

: 73426-02-5
4-(N-methylaminomethyl)-9-phenyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 74 percent / P₂S₅, NaHCO₃ / tetrahydrofuran / 3 h / Ambient temperature

2: 95 percent / K₂CO₃

3: toluene; pyridine / 0.5 h / Heating

4: 76 percent / 1) NaBH₄; 2) HCl

With hydrogenchloride; sodium tetrahydroborate; tetraphosphorus decasulfide; sodium hydrogencarbonate; potassium carbonate; In tetrahydrofuran; pyridine; toluene;
DOI:10.1248/cpb.32.877