5-(4-Chlorophenyl)-2,6-dimethyl-6,7-dihydro-1,3,4-oxadiazepine

Base Information

Chemical Name:5-(4-Chlorophenyl)-2,6-dimethyl-6,7-dihydro-1,3,4-oxadiazepine
CAS No.:92748-94-2
Molecular Formula:C₁₂H₁₃ClN₂O
Molecular Weight:236.701
Hs Code.:
DSSTox Substance ID:DTXSID20534155

Synonyms:92748-94-2;5-(4-Chlorophenyl)-2,6-dimethyl-6,7-dihydro-1,3,4-oxadiazepine;DTXSID20534155

Suppliers and Price of 5-(4-Chlorophenyl)-2,6-dimethyl-6,7-dihydro-1,3,4-oxadiazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-(4-Chlorophenyl)-2,6-dimethyl-6,7-dihydro-1,3,4-oxadiazepine

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:236.0716407
Heavy Atom Count:16
Complexity:306

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1COC(=NN=C1C2=CC=C(C=C2)Cl)C

Technology Process of 5-(4-Chlorophenyl)-2,6-dimethyl-6,7-dihydro-1,3,4-oxadiazepine

There total 4 articles about 5-(4-Chlorophenyl)-2,6-dimethyl-6,7-dihydro-1,3,4-oxadiazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 92749-05-8
Acetic acid 3-(4-chloro-phenyl)-2-methyl-3-oxo-propyl ester

: 64-19-7,77671-22-8
acetic acid

: 92748-94-2
5-(4-Chloro-phenyl)-2,6-dimethyl-6,7-dihydro-[1,3,4]oxadiazepine

Guidance literature:: With hydrazine hydrate; for 2h; Heating;
DOI:10.1055/s-1984-30838

Reference yield: 31.0%

: 6230-73-5
1-(4-chlorophenyl)-2-methylidenepropan-1-one

: 64-19-7,77671-22-8
acetic acid

: 92748-94-2
5-(4-Chloro-phenyl)-2,6-dimethyl-6,7-dihydro-[1,3,4]oxadiazepine

Guidance literature:: With hydrazine hydrate; for 2h; Heating;
DOI:10.1055/s-1984-30838

Reference yield:

: 6285-05-8
4'-chloropropiophenone

: 92748-94-2
5-(4-Chloro-phenyl)-2,6-dimethyl-6,7-dihydro-[1,3,4]oxadiazepine

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / aq. sodium hydroxide / 15 h / Ambient temperature

2: 31 percent / hydrazine hydrate / 2 h / Heating

With sodium hydroxide; hydrazine hydrate;
DOI:10.1055/s-1984-30838